ArticleWorld journal of surgery2021
Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma: A Case Controlled Study with Propensity Score Matching.
Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Laparoscopic versus open in right posterior sectionectomy: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- Feasibility of robotic liver resection compared with laparoscopic and open liver resection for hepatocellular carcinoma: a network meta-analysis.International journal of surgery (London, England) · 2026Article
- Association of operative approach with adverse events following hepatic resections.Surgery open science · 2025Article
- Implications of the surgical approach for complex liver resection in the era of enhanced recovery programs: a critical appraisal of the "Orange Segments" randomized controlled trial.Hepatobiliary surgery and nutrition · 2025Article
- Laparoscopic versus open surgery for liver resection: a multicenter cohort study.Scientific reports · 2024Article
- Minimally invasive versus open liver resection for hepatocellular carcinoma: a propensity score matching analysis of 224 patients.Langenbeck's archives of surgery · 2023Article
- Comprehensive analysis of laparoscopic, robotic, and open hepatectomy outcomes using the nationwide readmissions database.Journal of robotic surgery · 2022Article
- Letter to the Editor: Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma: A Case Controlled Study with Propensity Score Matching.World journal of surgery · 2021Article
- Authors' Reply: Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma: A Case Controlled Study with Propensity Score Matching.World journal of surgery · 2021Article
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13 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have suggested that laparoscopic liver resection (LLR) is associated with fewer postoperative complications than open liver resection (OLR) for hepatocellular carcinoma (HCC). However, this issue remains controversial since the data may have been attributable to an imbalance in patients' background.
methodsWe retrospectively analyzed 290 hepatectomies for HCC undertaken between 2011 and 2019. Liver resection difficulty was based on the 3 levels of the Institut Mutualiste Montsouris classification. Resection ratio was calculated using computed tomography volumetry. Patient characteristics were compared between the LLR and OLR groups. Propensity score matching (PSM) was adopted to adjust the imbalance between the cohorts, and the incidence of postoperative complications was compared.
resultsThe difficulty and resection ratio were significantly lower in LLR (n = 112) than in OLR (n = 178) (difficulty grade I/II/III: 84/10/18 vs. 43/39/96, p < 0.001; resection ratio: 11.4 ± 12.7 vs. 22.7 ± 17.2%, p < 0.001). The incidence of postoperative complications (Clavien-Dindo grade III or more) was lower in LLR (2.7% vs. 21.9%, p < 0.001), which was mainly attributable to fewer incidences of ascites and pleural effusion. PSM generated 68 well-matched patients in each group. The lower incidence of postoperative complications in LLR was also maintained in the PSM cohort (2.9% vs. 16.2%, p = 0.017). On multivariate analysis, LLR was the independent predictor of postoperative complications (OR 0.184, 95% CI 0.051-0.672, p = 0.010).
conclusionThe present study demonstrated that a laparoscopic approach reduces the incidence of postoperative complications in liver resection for HCC.
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