Evidence map›Paper›PMID 33881502›Full record

ArticleBlood2021

Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy in T-cell/histiocyte-rich large B-cell lymphoma.

Jonathan A Trujillo, James Godfrey, Yifei Hu, Jun Huang, Sonali M Smith, Matthew J Frigault, Zachariah DeFilipp, Daniel Appelbaum, Yonglin Pu, Nicholas Feinberg and 4 more

Open access · bronzeAbstract readComment
In one paragraph

Article in Blood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  13. CAR T-cell therapy in aggressive lymphomas-identifying prognostic and predictive markers.Hematology. American Society of Hematology. Education Program · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jonathan A TrujilloSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0002-0184-9773
James GodfreySection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0002-4103-4288
Yifei HuPritzker School of Medicine and.ORCID 0000-0003-2870-7772
Jun HuangPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL.ORCID 0000-0003-0271-4384
Sonali M SmithSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0002-9893-4949
Matthew J FrigaultDepartment of Medicine.
Zachariah DeFilippDepartment of Medicine.ORCID 0000-0002-7994-8974
Daniel AppelbaumDepartment of Radiology and.
Yonglin PuDepartment of Radiology and.ORCID 0000-0002-9583-8185
Nicholas FeinbergDepartment of Radiology and.
Thomas AlthausSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Michael R BishopSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Peter A RiedellSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0003-2719-0580
Justin KlineSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
University of Chicago · USMassachusetts General Hospital · US

Funding

MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
Developing an Oncology Workforce for the 21st Century - Renewal 01K12CA139160 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F., SMITH, SONALI · 2010 to 2024
$10.6M
NCI NIH HHS K12 CA139160NIGMS NIH HHS T32 GM007281
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphoma, Large B-Cell, DiffuseReceptors, Chimeric AntigenAntigens, CD19Cell- and Tissue-Based TherapyHistiocytesHumansImmunotherapy, AdoptiveT-LymphocytesAntigens, CD19Receptors, Chimeric Antigen

Identifiers

PMID33881502
PMCPMC8212512
OpenAlexW3153135411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.