ArticleNano letters2021
Nanodiamond Theranostic for Light-Controlled Intracellular Heating and Nanoscale Temperature Sensing.
Article in Nano letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Review
- Light-Harvesting Photothermal Hotspots Enabled by NIR Scattering-Absorption Coupling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Optically Detected Magnetic Resonance Based Intracellular Thermometry Using Nanodiamonds Implanted in Adherent Cancer Cells.ACS applied nano materials · 2026Article
- Small Particles, Big Impact: Inorganic Nanotechnology for Glioblastoma.Molecules (Basel, Switzerland) · 2026Review
- Single-Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Effect of H-Terminated Surfaces on "Silicon-Vacancy" Fluorescence in High-Pressure Nanodiamonds.Nanomaterials (Basel, Switzerland) · 2025Article
- Millikelvin Intracellular Nanothermometry with Nanodiamonds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Quantum relaxometry for detecting biomolecular interactions with single NV centers.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Tumor Spheroid Uptake of Fluorescent Nanodiamonds Is Limited by Mass Density: A 4D Light-Sheet Assay.Chemical & biomedical imaging · 2025Article
- Effects of Thermal Oxidation and Proton Irradiation on Optically Detected Magnetic Resonance Sensitivity in Sub-100 nm Nanodiamonds.ACS applied materials & interfaces · 2025Article
- Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Fluorescent Nanodiamonds for High-Resolution Thermometry in Biology.Nanomaterials (Basel, Switzerland) · 2024Review
- Advances of Fluorescent Nanodiamond Platforms for Intracellular and On-Chip Biosensing.Biosensors · 2024Review
- Review
- Unraveling Eumelanin Radical Formation by Nanodiamond Optical Relaxometry in a Living Cell.Journal of the American Chemical Society · 2024Article
- Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review.International journal of molecular sciences · 2023Review
- Sensing of Magnetic-Field Gradients with Nanodiamonds on Optical Glass-Fiber Facets.ACS applied nano materials · 2023Article
- Nanoscale thermal control of a single living cell enabled by diamond heater-thermometer.Scientific reports · 2023Article
- Diamond Relaxometry as a Tool to Investigate the Free Radical Dialogue between Macrophages and Bacteria.ACS nano · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temperature is an essential parameter in all biological systems, but information about the actual temperature in living cells is limited. Especially, in photothermal therapy, local intracellular temperature changes induce cell death but the local temperature gradients are not known. Highly sensitive nanothermometers would be required to measure and report local temperature changes independent of the intracellular environment, including pH or ions. Fluorescent nanodiamonds (ND) enable temperature sensing at the nanoscale independent of external conditions. Herein, we prepare ND nanothermometers coated with a nanogel shell and the photothermal agent indocyanine green serves as a heat generator and sensor. Upon irradiation, programmed cell death was induced in cancer cells with high spatial control. In parallel, the increase in local temperature was recorded by the ND nanothermometers. This approach represents a great step forward to record local temperature changes in different cellular environments inside cells and correlate these with thermal biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.