Evidence map›Paper›PMID 33880928›Full record

ArticleJournal of the American Heart Association2021

Hepatic Steatosis in Patients With Single Ventricle and a Fontan Circulation.

David A Katz, Daniel Peck, Adam M Lubert, Mathias Possner, Faizeen Zafar, Andrew T Trout, Joseph J Palermo, Nadeem Anwar, Jonathan R Dillman, Adam W Powell and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

David A KatzDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Daniel PeckDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Adam M LubertDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Mathias PossnerDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Faizeen ZafarDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Andrew T TroutDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Joseph J PalermoDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Nadeem AnwarDepartment of Gastroenterology University of Cincinnati Cincinnati OH.
Jonathan R DillmanDepartment of Radiology Cincinnati Children's Hospital Medical Center Cincinnati OH.
Adam W PowellDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Stavra A XanthakosDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Alexander R OpotowskyDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Gruschen VeldtmanKing Faisal Specialist Hospital and Research Centre Riyadh Saudi Arabia.
Tarek AlsaiedDepartment of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.
Cincinnati Children's Hospital Medical Center · USKing Faisal Specialist Hospital & Research Centre · SAUniversity of Cincinnati · USUniversity of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hepatic steatosis, caused by nonalcoholic fatty liver disease, is a leading cause of chronic liver disease. The interplay between hepatic steatosis and the development of liver disease following the Fontan procedure is not well understood. This study examined the prevalence and associations of hepatic steatosis in patients with a Fontan circulation. Methods and Results This was a single-center retrospective study of 95 patients with a Fontan circulation with liver magnetic resonance imaging performed between 2012 and 2019. The average age at magnetic resonance imaging was 21.5±8.5 years. The percent liver fat signal was determined using magnetic resonance chemical shift-encoded proton density fat fraction imaging. Hepatic steatosis was defined as liver fat ≥5% and was present in 10.5% of the cohort. The presence of hepatic steatosis was associated with higher body mass index (29±4 versus 24±6 kg/m

Indexed as

AdolescentAdultChildEchocardiographyFatty LiverFemaleFollow-Up StudiesFontan ProcedureHeart Defects, CongenitalHeart VentriclesHumansLiverMagnetic Resonance ImagingMaleMiddle AgedOhioabdominal fatadult congenital heart diseaseFontan associated liver diseaseFontan operationhepatic steatosisnonalcoholic fatty liver diseaseobesity

Identifiers

PMID33880928
PMCPMC8200742
OpenAlexW3155025577

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.