Evidence map›Paper›PMID 33880736›Full record

SynthesisAging clinical and experimental research2021

The effect of resistance training programs on lean body mass in postmenopausal and elderly women: a meta-analysis of observational studies.

Ewan Thomas, Ambra Gentile, Nemanja Lakicevic, Tatiana Moro, Marianna Bellafiore, Antonio Paoli, Patrik Drid, Antonio Palma, Antonino Bianco

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
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  8. Supervised resistance exercise for women with ovarian cancer who have completed first-line treatment: a pragmatic study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  9. Trial
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  11. High-speed resistance training vs. low-speed resistance training on body composition and physical function in adults with sarcopenic obesity.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  12. Review
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  18. Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ewan ThomasSport and Exercise Sciences Research Unit, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Ambra GentilePhD Program in Health Promotion and Cognitive Sciences, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Nemanja LakicevicPhD Program in Health Promotion and Cognitive Sciences, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Tatiana MoroDepartment of Biomedical Sciences, University of Padova, Via Marzolo 3, 35031, Padova, Italy. tatiana.moro@unipd.it.ORCID http://orcid.org/0000-0002-1404-1511
Marianna BellafioreSport and Exercise Sciences Research Unit, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Antonio PaoliDepartment of Biomedical Sciences, University of Padova, Via Marzolo 3, 35031, Padova, Italy.
Patrik DridFaculty of Sport and Physical Education, University of Novi Sad, Lovćenska 16, 2110, Novi Sad, Serbia.
Antonio PalmaSport and Exercise Sciences Research Unit, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Antonino BiancoSport and Exercise Sciences Research Unit, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging and menopause are associated with morphological and functional changes which may lead to loss of muscle mass and therefore quality of life. Resistance training (RT) is an effective training mode to increase muscle mass. We reviewed the existing literature to identify studies implementing RT protocols and evaluating muscle hypertrophy exclusively in healthy, postmenopausal and elderly women. Participants' age range was comprised between 50 and 80 years. The primary outcome observed was muscle hypertrophy. Fat mass was also evaluated, if available. PubMed and Web of Science were the screened database, and original articles written in English and published from 2000 up to 2020 were included. 26 articles were considered eligible and included. Quality assessment revealed a "moderate quality" of the included studies, however the majority of studies was able to reach level 4 of evidence and on overall grade of recommendation C. In total, data from 745 female participants subjected to different forms of resistance training were considered. Heterogeneity across studies was present regarding study design, intervention length (mean 16 weeks), training frequency (3 d/w), no. of exercises (n = 7.4) and participants' age (65.8 ± 4.9 years). Small-to-moderate significant increases (k = 43; SMD = 0.44; 95% CI 0.28; 0.60; p < 0.0001) of lean body mass were observed in post-menopausal and elderly women, regardless of age, intervention period, weekly training frequency and no. of exercises. No effects were noted for fat mass (k = 17; SMD = 0.27; 95% CI - 0.02; 0.55; p = 0.07). Studies need to concentrate on providing information regarding training parameters to more effectively counteract the effects of aging and menopause on skeletal muscle mass.

Indexed as

Resistance TrainingAgedAged, 80 and overExerciseFemaleHumansMuscle, SkeletalMuscle StrengthPostmenopauseQuality of LifeElderlyHypertrophyPost-menopausalResistance trainingWoman

Identifiers

PMID33880736
PMCPMC8595144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.