Evidence map›Paper›PMID 33880670›Full record

ArticleAIDS and behavior2021

A Prospective Study of Depressive Symptoms, Condomless Sex, and HIV Viral Load in HIV-Positive Female Sex Workers in Kenya.

Molly A Rosenthal, George Wanje, Barbra A Richardson, Juma Shafi, Lei Wang, Linnet Masese, Danielle N Poole, Walter Jaoko, Jane Simoni, R Scott Mcclelland

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Molly A RosenthalDepartment of General Internal Medicine, University of California, San Francisco, 1001 Portrero Ave, Box 0862, San Francisco, CA, 94110, USA. molly.rosenthal@ucsf.edu.ORCID http://orcid.org/0000-0002-5181-9644
George WanjeDepartment of Medicine, University of Washington, Seattle, USA.
Barbra A RichardsonDepartment of Biostatistics, University of Washington, Seattle, USA.
Juma ShafiDepartment of Medicine, University of Washington, Seattle, USA.
Lei WangDepartment of Global Health, University of Washington, Seattle, USA.
Linnet MaseseDepartment of Medicine, University of Washington, Seattle, USA.
Danielle N PooleDepartment of Medicine, University of Washington, Seattle, USA.
Walter JaokoDepartment of Medical Microbiology, University of Nairobi, Nairobi, Kenya.
Jane SimoniDepartment of Psychology, University of Washington, Seattle, USA.
R Scott McclellandDepartment of Medicine, University of Washington, Seattle, USA.
University of Washington · USUniversity of Nairobi · KEUniversity of California, San Francisco · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
Innate immune determinants of HIV rebound and persistenceR01HD103571 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JULIE M. OVERBAUGH · 2020 to 2026
$6.7M
Women's Life Events & HIV Transmission Potential: A Multidisciplinary StudyR01HD072617 · NICHD · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, RAYMOND SCOTT · 2012 to 2016
$2.1M
RCT of an Implementation Science Tool to Integrate HIV testing into Family Planning Services K24HD088229 · NICHD · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, RAYMOND SCOTT · 2016 to 2020
$863k
Center for AIDS Research, University of Washington P30 AI27757National Institute of Child Health and Human Development K24 088229National Institute of Child Health and Human Development R01 HD 072617NIAID NIH HHS P30 AI027757NICHD NIH HHS K24 HD088229NICHD NIH HHS R01 HD072617NICHD NIH HHS R01 HD103571
6 · The paper itself

Abstract

The relationships between depressive symptoms, viral suppression, and condomless sex were examined in a prospective cohort study of 369 HIV-positive Kenyan female sex workers. Participants were screened for depressive symptoms at baseline and every six months until completion of the study (up to 66 months). HIV viral load (VL) was measured every six months and prostate specific antigen (PSA) testing in vaginal secretions was performed quarterly. Mild or greater depressive symptoms were found in 100 (27.1%) women and were associated with increased risk of detectable VL (aRR 1.41, 95%CI 0.97-2.07, p-value = 0.07), but were not associated with detectable PSA. The co-occurrence of PSA detection and detectable VL at the same visit suggests the potential for HIV transmission but was uncommon (2.4% of visits). The prevalence of depressive symptoms and the association with detectable VL suggests the need for screening and treatment of depression for comprehensive HIV care in this population.

Indexed as

HIV InfectionsSex WorkersDepressionFemaleHumansKenyaMaleProspective StudiesUnsafe SexViral LoadDepressionDepressive symptomsHIVHIV-positive female sex workersTransmission risk

Identifiers

PMID33880670
PMCPMC9211371
OpenAlexW3155568306

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.