Evidence map›Paper›PMID 33880461›Full record

ArticleColorado journal of psychiatry & psychology2017

Sleep Spindles and Auditory Sensory Gating: Two Measures of Cerebral Inhibition in Preschool-Aged Children are Strongly Correlated.

Peng-Peng Wei, Sharon K Hunter, Randal G Ross

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Colorado journal of psychiatry & psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Peng-Peng WeiDivision of Child and Adolescent Psychiatry, Department of Psychiatry, University of Colorado School of Medicine, Pediatric Mental Health Institute, Children's Hospital Colorado. Dr Wei is currently at New York Presbyterian Hospital, New York, New York. Dr Hunter is currently residing in Houston, TX.
Sharon K HunterDivision of Child and Adolescent Psychiatry, Department of Psychiatry, University of Colorado School of Medicine, Pediatric Mental Health Institute, Children's Hospital Colorado. Dr Wei is currently at New York Presbyterian Hospital, New York, New York. Dr Hunter is currently residing in Houston, TX.
Randal G RossDivision of Child and Adolescent Psychiatry, Department of Psychiatry, University of Colorado School of Medicine, Pediatric Mental Health Institute, Children's Hospital Colorado. Dr Wei is currently at New York Presbyterian Hospital, New York, New York. Dr Hunter is currently residing in Houston, TX.
New York Hospital Queens · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Colorado Clinical and Translational Science Institute (UL1)UL1TR000154 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2012 to 2013
$20.4M
STATISTICAL GENETICS AND TREATMENT ANALYSISP50MH086383 · NIMH · UNIVERSITY OF COLORADO DENVER · PI FREEDMAN, ROBERT R · 2009 to 2013
$10.6M
SMOOTH PURSUIT EYE MOVEMENTS--CHILDREN OF SCHIZOPHRENICSR01MH056539 · NIMH · UNIVERSITY OF COLORADO DENVER · PI ROSS, RANDAL G · 1997 to 2008
$1.8M
Training Medical Students to Become Child PsychiatristsR25MH080859 · NIMH · UNIVERSITY OF COLORADO DENVER · PI ROSS, RANDAL G · 2007 to 2011
$649k
Attention and Smooth Pursuit in Infants with a Family History of PsychosisR03HD058033 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HUNTER, SHARON K · 2009 to 2010
$153k
NCATS NIH HHS UL1 TR000154NCRR NIH HHS UL1 RR025780NICHD NIH HHS R03 HD058033NIMH NIH HHS P50 MH086383NIMH NIH HHS R01 MH056539NIMH NIH HHS R25 MH080859
6 · The paper itself

Abstract

introductionSleep spindles and P50 sensory gating are both reflective of cerebral inhibition, however, are differentially active during different phases of sleep. Assessing whether sleep spindles and P50 sensory gating correlate is a first step to evaluate whether these 2 forms of cerebral inhibition reflect overlapping neural circuits.

methodsEEG data were collected between midnight and 6:00 AM on 13 healthy preschool-aged children. P50 sensory gating, calculated during REM sleep, negatively correlated with spindle duration (r=-.715, p=.006) and inter-peak density (r=.744, p=.004). There was a trend toward higher S2/S1 ratios being associated with fewer peaks per spindle (r=-.546, p=.053). In 4-year-olds, 2 established physiological measures of sensory gating and are correlated despite being maximally active during different stages of sleep.

conclusionsThese results suggest there is an overlap in brain mechanisms underlying each gating mechanism.

Identifiers

PMID33880461
PMCPMC8055067
OpenAlexW3155008170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.