Evidence map›Paper›PMID 33880442›Full record

ArticleJournal of translational autoimmunity2021

Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms.

Gerd Wallukat, Bettina Hohberger, Katrin Wenzel, Julia Fürst, Sarah Schulze-Rothe, Anne Wallukat, Anne-Sophie Hönicke, Johannes Müller

Open access · goldAbstract read
In one paragraph

Article in Journal of translational autoimmunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 220 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
220citing papers in PubMed, 3 pooled it
31.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

220 citing papers in PubMed, 3 syntheses or guidelines pooled it, 360 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Post-COVID Syndrome.Deutsches Arzteblatt international · 2023
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

160 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gerd WallukatExperimental and Clinical Research Center, Charité Campus Buch, Max-Delbrück Center for Molecular Medicine, Berlin, Germany.
Bettina HohbergerDepartment of Ophthalmology, University of Erlangen, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.
Katrin WenzelBerlin Cures GmbH, Berlin; Germany.
Julia FürstDepartment of Medicine 1, University Hospital Erlangen, Erlangen, Germany.
Sarah Schulze-RotheBerlin Cures GmbH, Berlin; Germany.
Anne WallukatBerlin Cures GmbH, Berlin; Germany.
Anne-Sophie HönickeBerlin Cures GmbH, Berlin; Germany.
Johannes MüllerBerlin Cures GmbH, Berlin; Germany.
Berlin Heart (Germany) · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impairment of health after overcoming the acute phase of COVID-19 is being observed more and more frequently. Here different symptoms of neurological and/or cardiological origin have been reported. With symptoms, which are very similar to the ones reported but are not caused by SARS-CoV-2, the occurrence of functionally active autoantibodies (

Indexed as

ACE2, Angiotensin-converting enzyme 2 receptorsAT1-fAAB, Autoantibody targeting the angiotensin II AT1 receptorAutoantibodyAutoimmunityCOVID-19CRPS, Complex regional pain syndromeETA-fAAB, Autoantibody targeting the endothelin receptorfAAB, Functional autoantibodyFatigueGPCR, G-protein coupled receptorsLong-COVIDM2-fAAB, Autoantibody targeting the muscarinic receptorMAS-fAAB, Autoantibody targeting the MAS receptorNOC-fAAB, Functionally active autoantibody against the nociceptin receptorPost-covid-19 symptomPoTS, Postural orthostatic tachycardia syndromeRAS, Renin angiotensin systemSARS, Severe acute respiratory syndromeα1-fAAB, Autoantibody targeting the alpha1-adrenoceptorβ2-fAAB, Autoantibody targeting the beta2-adrenoceptor

Identifiers

PMID33880442
PMCPMC8049853
OpenAlexW3155272051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.