Evidence map›Paper›PMID 33880422›Full record

ReviewHeliyon2021

The role of nanotechnology in current COVID-19 outbreak.

Shima Tavakol, Masoumeh Zahmatkeshan, Reza Mohammadinejad, Saeed Mehrzadi, Mohammad T Joghataei, Mo S Alavijeh, Alexander Seifalian

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Low-cost zeolitic carriers for delivery of hydroxychloroquine immunomodulatory agent with antiviral activity.Microporous and mesoporous materials : the official journal of the International Zeolite Association · 2022
    Article
  5. Antiviral potential of nanoparticles for the treatment of Coronavirus infections.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Review
  6. Review
  7. Review
  8. Review
  9. A comprehensive review on efficient approaches for combating coronaviruses.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shima TavakolCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Masoumeh ZahmatkeshanCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Reza MohammadinejadResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran.
Saeed MehrzadiRazi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mohammad T JoghataeiCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mo S AlavijehPharmidex Pharmaceutical Services Ltd., London, United Kingdom.
Alexander SeifalianNanotechnology and Regenerative Medicine Commercialization Centre (NanoRegMed Ltd, UK), London BioScience Innovation Centre, London, NW1 0NH, United Kingdom.
Iran University of Medical Sciences · IRKerman University of Medical Sciences · IRLondon Centre for Nanotechnology · GBPharmidex (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 has recently become one of the most challenging pandemics of the last century with deadly outcomes and a high rate of reproduction number. It emphasizes the critical need for the designing of efficient vaccines to prevent virus infection, early and fast diagnosis by the high sensitivity and selectivity diagnostic kits, and effective antiviral and protective therapeutics to decline and eliminate the viral load and side effects derived from tissue damages. Therefore, non-toxic antiviral nanoparticles (NPs) have been under development for clinical application to prevent and treat COVID-19. NPs showed great promise to provide nano vaccines against viral infections. Here, we discuss the potentials of NPs that may be applied as a drug itself or as a platform for the aim of drug and vaccine repurposing and development. Meanwhile, the advanced strategies based on NPs to detect viruses will be described with the goal of encouraging scientists to design effective and cost-benefit nanoplatforms for prevention, diagnosis, and treatment.

Indexed as

CellsClinicalCoronavirusCOVID-19Drug deliveryDrug repurposingNanocarrierNanomaterialsNanoparticleNanotechnologyPreclinicalVaccine

Identifiers

PMID33880422
PMCPMC8049405
OpenAlexW3155973369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.