Evidence map›Paper›PMID 33880412›Full record

ArticleBMJ open ophthalmology2021

Anti-inflammatory treatment after cataract surgery in Sweden: changes in prescribing patterns from 2010 to 2017.

Behrad Samadi, Mats Lundstrom, Madeleine Zetterberg, Ingela Nilsson, Per Montan, Anders Behndig, Maria Kugelberg

Open access · goldAbstract read
In one paragraph

Article in BMJ open ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Behrad SamadiDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden behrad.samadi@ki.se.ORCID http://orcid.org/0000-0002-8578-8209
Mats LundstromDepartment of Clinical Sciences, Ophthalmology, Faculty of Medicine, Lund University, Karlskrona, Sweden.
Madeleine ZetterbergDepartment of Clinical Neuroscience, University of Gothenburg, Mölndal, Sweden.
Ingela NilssonCapio Medocular AB, Malmö, Sweden.
Per MontanDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Anders BehndigRC Syd, Blekinge Hospital Karlskrona, Karlskrona, Sweden.
Maria KugelbergDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Karolinska Institutet · SEBlekinge Institute of Technology · SELund University · SESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate changes in the prescribing patterns of postoperative eye drops following cataract surgery in Sweden from 2010 to 2017.

methodsData from cataract procedures registered in the National Cataract Register during the month of March from 2010 to 2017 were record linked and sent to the Swedish Prescribed Drug Register, which allowed us to determine which eye drops the patients had obtained from 3 months presurgery to 2 weeks post surgery.

resultsDuring the 8-year study period, 54 889 surgeries were registered. Combination treatment with steroid and non-steroidal anti-inflammatory drug (NSAID) eye drops increased from 12% in 2010 to 60% in 2017 (p<0.001) while monotherapy with steroids decreased from 71% in 2010 to 26% in 2017 (p<0.001). Monotherapy with NSAIDs after surgery was fairly stable, at 17% in 2010 and 13% in 2017 (p<0.001). Combination treatment was more frequent in patients with diabetic retinopathy (p<0.001) or age-related macular degeneration (p<0.001), while monotherapy with steroids was more frequent in patients with glaucoma (p<0.001). The proportion of monotherapy or combination therapy varied widely between ophthalmic clinics. The prescription of antibiotic eye drops after surgery also varied greatly between clinics, from 0% to 63%, with a national average of 4.9%.

conclusionThere is a change in the prescription pattern of anti-inflammatory eye drops after cataract surgery in Sweden, with less monotherapy and an increasing proportion of patients receiving a combination of steroid and NSAID eye drops.

Indexed as

inflammationtreatment medicaltreatment surgery

Identifiers

PMID33880412
PMCPMC7993195
OpenAlexW3138738839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.