Evidence map›Paper›PMID 33880250›Full record

ArticleCureus2021

The Association of Acute Kidney Injury With Disease Severity and Mortality in COVID-19: A Systematic Review and Meta-Analysis.

Trishala Menon, Rohit Sharma, Saurabh Kataria, Sundus Sardar, Ramesh Adhikari, Sohaib Tousif, Hira Khan, Sawai Singh Rathore, Romil Singh, Zahoor Ahmed

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Trishala MenonFamily Medicine, Wheeling Hospital, Wheeling, USA.
Rohit SharmaInternal Medicine, Hamad Medical Corporation, Doha, QAT.
Saurabh KatariaNeurology and Neurocritical Care, University of Missouri Health Care, Columbia, USA.
Sundus SardarInternal Medicine, Hamad Medical Corporation, Doha, QAT.
Ramesh AdhikariHospital Medicine, Franciscan Health, Lafayette, USA.
Sohaib TousifMedicine, Ziauddin University, Karachi, PAK.
Hira KhanInternal Medicine, Islamic International Medical College, Rawalpindi, PAK.
Sawai Singh RathoreInternal Medicine, Dr. Sampurnanand Medical College, Jodhpur, IND.
Romil SinghCritical Care, Mayo Clinic, Rochester, USA.
Zahoor AhmedInternal Medicine, King Edward Medical University, Mayo Hospital, Lahore, PAK.
Hamad Medical Corporation · QABrown University · USDinajpur Medical College · BDMayo Clinic in Florida · USUniversity of Missouri Health System · USWheeling Hospital · USZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective The coronavirus disease 2019 (COVID-19) pandemic has become a global healthcare emergency. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, has a wide range of clinical manifestations ranging from subclinical infection to multi-organ failure. In addition to the respiratory system, COVID-19 also adversely affects the kidneys. In this study, we aimed to measure the prevalence of acute kidney injury (AKI) in COVID-19 and its association with the disease severity and mortality in COVID-19 patients. Materials and methods We conducted our study by following the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) guidelines. A comprehensive literature search using four databases (PubMed, EMBASE, Google Scholar, and clinicaltrial.gov) was performed. Our initial search returned 2,771 articles. After excluding review articles, duplicates, and non-relevant studies, we included 20 articles that reported an association between COVID-19 and AKI. We subsequently performed a random effect analysis to find the pooled prevalence, pooled odds ratio (OR) estimates, and 95% confidence intervals for severe COVID-19 and mortality outcomes in AKI using Cochrane RevMan (version 5.4) and R programming language (version 4.16-2). Results A total of 14,415 patients from various countries were included. Among the 20 cohorts, the median age was 55.8 ±8.39 years (range: 43-72 years), and 43.78% of the subjects were female. Out of a total of 14,415 patients, 3,820 developed AKI with a pooled prevalence of 11% (95% CI: 0.07-0.15; p<0.01; I

Indexed as

acute kidney injuryacute renal failurecovid-19sars-cov-2

Identifiers

PMID33880250
PMCPMC8045562
OpenAlexW3137393398

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.