ArticleCureus2021
Excited Catatonia - A Delayed Neuropsychiatric Complication of COVID-19 Infection.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology.Journal of psychopharmacology (Oxford, England) · 2023Guideline
- COVID-19-associated psychosis: A systematic review of case reports.General hospital psychiatryPooled it
- Postpartum delirious mania in a patient with diagnosis of bipolar disorder after cesarean delivery: a case report.Frontiers in psychiatry · 2026Article
- (COVID-19) SARS-CoV-2-catatonia syndrome: does it exist? Longitudinal evidence.Frontiers in psychiatry · 2026Article
- Facing the Shadow Pandemic: Correlation and Trend Analyses of Violence Reports from Women to the Italian National Anti-Violence Number during 2021.Healthcare (Basel, Switzerland) · 2023Article
- Catatonia after COVID-19 infection: scoping review.BJPsych bulletin · 2023Article
- Delayed onset catatonia after COVID-19.Psychiatry research case reports · 2022Article
- Complex Hallucinations in Hospitalized Rehabilitation Patients With COVID-19.Archives of rehabilitation research and clinical translation · 2022Article
- Post-COVID-19 Suicide Note: A Case Report of Late Onset Catatonia.Psychiatry and clinical psychopharmacology · 2022Article
- Molecular and cellular mechanisms leading to catatonia: an integrative approach from clinical and preclinical evidence.Frontiers in molecular neuroscience · 2022Review
- Postinfectious COVID-19 Catatonia: A Report of Two Cases.Frontiers in psychiatry · 2021Article
- Clinical Features of First-episode Psychoses During the COVID-19 Pandemic.Consortium psychiatricum · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of patients have been presenting with neuropsychiatric signs and symptoms associated with coronavirus disease (COVID-19). We present a case of a 69-year-old female with no prior psychiatric history who was brought to the emergency department due to bizarre behavior and paranoid thoughts for four to six weeks, worsening over the last two weeks. Psychiatric evaluation found that the patient had extreme restlessness and agitation, poor eye contact, paranoid delusions, visual hallucinations, and a flat affect with stereotypic repetition of speech and loose associations. The patient's family noted that two months prior she had symptoms of common cold associated with a severe cough and 20 pounds of weight loss. Suspicion for prior COVID-19 infection prompted an IgG antibody test, which was positive. Our patient displayed at least three of the signs needed to diagnose catatonia - agitation, rigidity, and echolalia - and had a therapeutic response to lorazepam, confirming suspicions of excited catatonia. Her seropositivity for IgG against COVID-19 suggested a COVID-induced brief psychotic disorder with catatonia, which makes this the first known case, to our knowledge, of a patient with delayed onset catatonia after COVID-19 infection. This suggests that clinicians should, after ruling out more plausible stressors, suspect possible coronavirus involvement in sudden onset psychotic disorders, especially in patients who do not fit the demographic of new-onset schizophrenia-spectrum diagnoses. Further research is needed on the pathophysiology behind COVID-19 altering neuronal function and neurotransmitter pathways.
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