SynthesisJournal of global health2021
The global prevalence of essential tremor, with emphasis on age and sex: A meta-analysis.
Synthesis in Journal of global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Update on Medical Treatments for Essential Tremor: An International Parkinson and Movement Disorder Society Evidence-Based Medicine Review.Movement disorders : official journal of the Movement Disorder Society · 2026Pooled it
- Diagnostic Accuracy of the Archimedes Spiral Test for Essential Tremor: A Meta-Analysis.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Pooled it
- Efficacy and Safety of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Systematic Review and Metanalysis.Movement disorders : official journal of the Movement Disorder Society · 2025Pooled it
- Vitamin D supplementation in later life: a systematic review of efficacy and safety in movement disorders.Frontiers in aging neuroscience · 2024Pooled it
- Comparative Effectiveness of Transcutaneous Afferent Patterned Stimulation Therapy for Essential Tremor: A Randomized Pragmatic Clinical Trial.Tremor and other hyperkinetic movements (New York, N.Y.) · 2023Trial
- Evaluation of Autonomic and Cognitive Functions in Patients with Essential Tremor.Neurology and therapy · 2026Article
- Association between mild action tremor and cognition in community dwelling older adults: results from the KORA-Age study.Journal of neurology · 2026Article
- The JAK1/2 Inhibitor Baricitinib Ameliorates Neuroinflammation and Symptoms in an Animal Model of Essential Tremor.Pharmacology research & perspectives · 2026Article
- Gamma knife thalamotomy for essential tremor in the third era of functional neurosurgery.Neurosurgical review · 2026Observational
- Rescue deep brain stimulation for recurrent essential tremor after ventral intermediate nucleus thalamotomy: illustrative cases.Journal of neurosurgery. Case lessons · 2026Article
- Epidemiology and Treatment of Patients with Essential Tremor: A Retrospective Cohort Analysis in the United Kingdom.Neuroepidemiology · 2026Article
- Article
- Reduced Mitochondrial DNA Copy Number and Telomere Length in Essential Tremor Patients: Evidence from an Age- and Sex-Adjusted Cross-Sectional Case-Control Study.International journal of molecular sciences · 2026Article
- Prevalence of Essential Tremor among Greeks Aged 65 Years or Older: Results from the HELIAD Study.Neuroepidemiology · 2026Article
- Focused ultrasound thalamotomy improves voice tremor in essential tremor: objective insight from artificial intelligence.Scientific reports · 2026Article
- Essential Tremor Cases with Subtle Cerebellar Pathology: A Systematic Study of Postmortem Cerebellar Changes.Cerebellum (London, England) · 2026Article
- Wearable Ultrasound Sensing with Dual Arrays and Machine Learning for Real-Time Tremor Characterization and Antagonist Muscle Monitoring.IEEE transactions on instrumentation and measurement · 2026Article
- An Exploratory Analysis of Essential Tremor and Associated Phenotypes.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Prevalence of Diagnosed Essential Tremor Using Electronic Healthcare Records: A Population-Based Study in Northeast-Central Pennsylvania.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Objective tremor monitoring using tri-axis accelerometer in MRgFUS thalamotomy for essential tremor: a feasibility study.Therapeutic advances in neurological disorders · 2026Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEssential tremor (ET) is one of the most common neurological disorders that impairs quality of life and leads to disability and social handicap. It was estimated that approximate 0.9% of people worldwide were affected by ET. The last decade has seen new investigations on the epidemiology of ET, enabling us to provide an up-to-date estimation of ET prevalence, with emphasis on age and sex.
methodsWe searched PubMed, Medline, Embase and Global Health for studies that reported the prevalence of ET in the general population. Potential sources of heterogeneity were examined by age-adjusted meta-regression. The age- and sex-specific prevalence of ET was constructed with a multilevel mixed-effects meta-regression.
resultsA total of 29 articles were included in our systematic review and meta-analysis. The prevalence of ET increased dramatically with advancing age, where the prevalence estimate in people aged under 20 years was 0.04% (95% confidence interval [CI] = 0.00-0.29) and that in elderly aged 80 years and above was 2.87% (95% CI = 1.07-7.49). ET was consistently more common in males than in females. In 2020, the overall prevalence of ET in the general population was 0.32% (95% CI = 0.12-0.91), and the prevalence was higher in males (0.36%, 95% CI = 0.14-1.03) than in females (0.28%, 95% CI = 0.11-0.79). In 2020, the number of people affected by ET was 24.91million (95% CI = 9.51-70.92), among whom 56% were males.
conclusionsThis study provides an up-to-date estimation of ET prevalence in the general population throughout the whole life span, with emphasis on age and sex. The adoption of an internationally acknowledged diagnostic strategy is prompted in future epidemiological investigations. PROTOCOL REGISTRATION: PROSPERO (CRD42020203979).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.