ArticleJournal of clinical biochemistry and nutrition2021
Oleic acid to stearic acid ratio might be a potential marker for insulin resistance in non-obese Japanese.
Article in Journal of clinical biochemistry and nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- The effect of oleic acid enriched diets on glucose and lipid metabolism: a systematic review and meta-analysis.Nutrition & metabolism · 2026Article
- Mini-review on insulin resistance assessment: Advances in surrogate indices and clinical applications.World journal of clinical cases · 2025Review
- Analysis of the Correlation between Cholesterol Levels in Blood Using Clinical Data and Hair Using Mass Spectrometry Imaging.Mass spectrometry (Tokyo, Japan) · 2024Article
- Estimated Elovl6 and delta-5 desaturase activities might represent potential markers for insulin resistance in Japanese adults.Journal of diabetes and metabolic disorders · 2022Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
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Abstract
Results from a recent study indicate that a higher level of oleic acid/stearic acid ratio was associated with metabolically unhealthy obesity. This was further validated in cross-sectional and interventional studies; however, this was not extensively studied in a non-obese population. We recruited 260 Japanese subjects with serum free fatty acid profiles undergoing anti-aging health examinations. The determinants for oleic acid/stearic acid ratio were investigated using multiple regression analyses. To compare different markers, the subjects were classified based on oleic acid/stearic acid ratio and the combination of oleic acid/stearic acid ratio and triglyceride levels. The oleic acid/stearic acid ratio exhibited a positive correlation with the logmatic transformed triglyceride/high-density lipoprotein cholesterol ratio and the fasting triglycerides-glucose index, both of which were used as markers for insulin resistance. Multiple regression analyses revealed that the triglyceride/high-density lipoprotein cholesterol ratio and fasting triglyceride-glucose index were positively associated with the oleic acid/stearic acid ratio. Most markers were the worst in the highest triglyceride group in both oleic acid/stearic acid groups. In addition, most markers were worse in high oleic acid/stearic acid ratio group than low group. In conclusion, oleic acid/stearic acid ratio might be a useful marker for insulin resistance in non-obese Japanese subjects.
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