Evidence map›Paper›PMID 33879902›Full record

Trial reportBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2021

[Clinical value of inflammatory biomarkers in predicting prognosis of patients with ureteral urothelial carcinoma].

H A Chen, S Liu, X J Li, Z Wang, C Zhang, F Q Li, W L Miao

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

H A ChenDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
S LiuDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
X J LiDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
Z WangDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
C ZhangDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
F Q LiDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
W L MiaoDepartment of Urology, the First Affiliated Hospital, Hebei North Univercity, Zhangjiakou 075061, Hebei, China.
Hebei North University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical value of inflammation-related markers in predicting the prognosis of patients with ureteral urothelial carcinoma.

methods200 patients with ureteral urothelial carcinoma were randomly divided into two groups by split sample validation: modeling group and validation group. Paraffin embedded pathological specimens of the patients were reviewed. Immunohistochemical method was used to detect tumor-infiltrating neutrophil (TIN) (CD66b

resultsThe median follow-up time was 36 months, the progression-free survival was 40 months, and 42 cases (21.0%) showed tumor progression within 3 years. Tumor size, pathological stage and pathological grade were all single-factor variables predicting the first recurrence of ureteral urothelial carcinoma three years after operation. Tumor size, pathological stage, pathological grade, TIN, TAM, NLR and NMR were multi-factor variables predicting the first recurrence three years after operation. Among 104 cases of non-muscle-invasive ureteral urothelial carcinoma, 10 cases (9.6%) recurred for the first time 3 years after operation, 96 cases (33.3%) of muscle invasive ureteral urothelial carcinoma, and the diffe-rence between the two groups was statistically significant (

conclusionThe prognosis prediction model based on immune inflammation-related markers was established as a perfection and supplement for the existing pathological grading and staging system, providing a basis for accurate individualized treatment of patients with urete-ral urothelial carcinoma. The prognosis prediction model based on the relevant indicators of peripheral blood samples is established, which is easy to obtain specimens, and the detection method is simple and economical, which is more conducive to clinical application.

Indexed as

Carcinoma, Transitional CellUreteral NeoplasmsBiomarkersHumansNeoplasm Recurrence, LocalPrognosisRetrospective StudiesTumor MicroenvironmentBiomarkersBiomarkersInflammationLinear modelsPrognosisUreteral neoplasms

Identifiers

PMID33879902
PMCPMC8072417
OpenAlexW3154016664

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.