Evidence map›Paper›PMID 33879892›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2021

[Effects of ultrafine particulates on cardiac function in rat isolated heart].

F Bai, Y F He, Y N Niu, R J Yang, J Cao

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

F BaiDepartment of Cardiology, The First Hospital of Shanxi Medical University & Department of Pharmacology, Basic Medical School, Shanxi Medical University, Taiyuan 030001, China.
Y F HeDepartment of Cardiology, The First Hospital of Shanxi Medical University & Department of Pharmacology, Basic Medical School, Shanxi Medical University, Taiyuan 030001, China.
Y N NiuDepartment of Cardiology, The First Hospital of Shanxi Medical University & Department of Pharmacology, Basic Medical School, Shanxi Medical University, Taiyuan 030001, China.
R J YangDepartment of Cardiology, The First Hospital of Shanxi Medical University & Department of Pharmacology, Basic Medical School, Shanxi Medical University, Taiyuan 030001, China.
J CaoDepartment of Cardiology, The First Hospital of Shanxi Medical University & Department of Pharmacology, Basic Medical School, Shanxi Medical University, Taiyuan 030001, China.
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether ultrafine particulates (UFPs) have direct deleterious effects on cardiac function through activating MAPK signaling.

methodsLangendorff-perfused Sprague-Dawley rat hearts were randomly divided into 2 groups (

resultsNo significant changes in cardiac function were detected before and after the perfusion in control group while UFPs perfused hearts showed a decline in cardiac function in a time-dependent manner (all

conclusionThe results of this study demonstrated that the short-term exposure of UFPs to the isolated rat hearts has direct and acute toxic effects on cardiac function, probably related to attenuation of anti-oxidative capacity and activation of MAPK signaling pathways.

Indexed as

HeartMyocardiumAnimalsMalondialdehydeOxidative StressRatsRats, Sprague-DawleyMalondialdehydeIsolated rat heartMAPKOxidative stressUltrafine particulates(UFPs)

Identifiers

PMID33879892
PMCPMC8072420
OpenAlexW3156198677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.