Evidence map›Paper›PMID 33879686›Full record

ArticleMedicine2021

Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis.

Xiaofeng Li, Xianghai Gan, Junzuo Gong, Tianyi Mou, Hua Zhou, Mengqin Li

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaofeng LiDepartment of Emergency.
Xianghai GanDepartment of Emergency.
Junzuo GongDepartment of Emergency.
Tianyi MouDepartment of Emergency.
Hua ZhouDental Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan Province, China.
Mengqin LiDepartment of Emergency.ORCID 0000-0002-3339-2413
North Sichuan Medical University · CN

Funding

Science and Technology Strategy Cooperation Project of Nanchong City School 19SXHZ0056
6 · The paper itself

Abstract

backgroundSeveral studies have been performed to investigate the association between vitamin D receptor (VDR) gene polymorphism and acute pancreatitis, but the results are inconclusive. We conducted this meta-analysis for a precise estimation of the association between BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), and FokI (rs2228570) polymorphisms and acute pancreatitis.

methodsAppropriate studies were retrieved by searching Web of Science, PubMed, Scopus, and Google scholar databases, until January 31, 2021. Two reviewers independently conducted data extraction and literature quality evaluation. Odds ratios and 95% confidence intervals were calculated to evaluate the strength of the association.All of the data were analyzed with Stata 16.0.

resultsThe results of this meta-analysis will be submitted to a peer-reviewed journal for publication.

conclusionsThis meta-analysis will summarize the association between BsmI, ApaI, TaqI, and FokI polymorphisms and the risk of acute pancreatitis. ETHICS AND DISSEMINATION: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/83W7R.

Indexed as

Genetic Predisposition to DiseaseHumansMeta-Analysis as TopicOdds RatioPancreatitisPolymorphism, Restriction Fragment LengthReceptors, CalcitriolRisk FactorsSystematic Reviews as TopicReceptors, CalcitriolVDR protein, human

Identifiers

PMID33879686
PMCPMC8078433
OpenAlexW3155272462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.