Evidence map›Paper›PMID 33879591›Full record

ArticlemBio2021

NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target.

Samuel Fenn, Jean-Frédéric Dubern, Cristina Cigana, Maura De Simone, James Lazenby, Mario Juhas, Stephan Schwager, Irene Bianconi, Gerd Döring, Jonas Elmsley and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Redox protection by bacterial glutathione peroxidase drives virulence inRedox report : communications in free radical research · 2026
    Article
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  3. Article
  4. Metabolic reprogramming promotesMicrobiology (Reading, England) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Nitrate reduction salvage pathway inFrontiers in microbiology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Samuel FennNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom Samuel.fenn1@nottingham.ac.uk Miguel.Camara@nottingham.ac.uk.ORCID 0000-0002-0522-8894
Jean-Frédéric DubernNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-9951-6925
Cristina CiganaDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-0436-9721
Maura De SimoneDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
James LazenbyNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Mario JuhasDepartment of Microbiology, Institute of Plant Biology, University of Zürich, Zürich, Switzerland.
Stephan SchwagerDepartment of Microbiology, Institute of Plant Biology, University of Zürich, Zürich, Switzerland.
Irene BianconiDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Gerd DöringInstitute of Medical Microbiology and Hygiene, University of Tübingen, Tübingen, Germany.
Jonas ElmsleyNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Leo EberlDepartment of Microbiology, Institute of Plant Biology, University of Zürich, Zürich, Switzerland.ORCID 0000-0002-7241-0864
Paul WilliamsNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-1920-5036
Alessandra BragonziDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-5808-7669
Miguel CámaraNational Biofilms Innovation Centre, Nottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom Samuel.fenn1@nottingham.ac.uk Miguel.Camara@nottingham.ac.uk.ORCID 0000-0003-4585-7385
University of Nottingham · GBVita-Salute San Raffaele University · ITUniversity of Zurich · CHInstitute of Medical Microbiology and Hygiene · DE

Funding

Biotechnology and Biological Sciences Research Council BB/R012415/1Wellcome Trust 108876/Z/15/Z
6 · The paper itself

Abstract

The opportunistic pathogen

Indexed as

AmmoniaAnimalsBacterial ProteinsCaenorhabditis elegansCell LineDisease Models, AnimalDrosophila melanogasterFerredoxinsGene LibraryHumansMaleMiceMice, Inbred C57BLMutationNitrite ReductasesPseudomonas aeruginosaAmmoniaBacterial ProteinsFerredoxinsNitrite ReductasesVirulence Factorsdisease modeldisease modelsgenome-wide screeningnitrite reductasePseudomonas aeruginosatransposon mutagenesisvirulence determinantsvirulence target

Identifiers

PMID33879591
PMCPMC8092218
OpenAlexW3156544026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.