Evidence map›Paper›PMID 33879588›Full record

ArticlemBio2021

Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of

Robert C Kauffman, Oluwaseyi Adekunle, Hanyi Yu, Alice Cho, Lindsay E Nyhoff, Meagan Kelly, Jason B Harris, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Stephen B Calderwood and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. EPY001, a Novel Monoclonal Antibody AgainstInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Dynamics of IgM and IgA Antibody Response Profile AgainstInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Virus-like Particle Display ofACS infectious diseases · 2022
    Article
  8. Article
  9. Article
  10. Systemic, Mucosal, and Memory Immune Responses following Cholera.Tropical medicine and infectious disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Robert C Kauffman *Division of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Oluwaseyi Adekunle *Division of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Hanyi YuDepartment of Computer Science, Emory University, Atlanta, Georgia, USA.
Alice ChoDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Lindsay E NyhoffDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Meagan KellyDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jason B HarrisDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Taufiqur Rahman BhuiyanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Firdausi QadriInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Stephen B CalderwoodDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-8881-1849
Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jun KongDepartment of Computer Science, Emory University, Atlanta, Georgia, USA.
Jens WrammertDivision of Infectious Disease, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA jwramme@emory.edu.ORCID 0000-0002-1733-4424
Emory University · USHarvard University · USInternational Centre for Diarrhoeal Disease Research · BDMassachusetts General Hospital · US

Funding

Training a New Generation of VaccinologistsT32AI074492 · NIAID · EMORY UNIVERSITY · PI Rama Rao Amara, Benjamin A Lopman · 2009 to 2026
$6.4M
Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
O-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1M
Antibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9M
Innate and early B cell responses to V. choleraeR01AI103055 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B · 2014 to 2018
$3.9M
O-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7M
Human B cell responses to a live attenuated cholera vaccineR01AI137127 · NIAID · EMORY UNIVERSITY · PI WRAMMERT, JENS PETER · 2018 to 2022
$1.9M
O-Specific Polysaccharide Responses and CholeraR56AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2013 to 2020
$843k
Humoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359k
FIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362NIAID NIH HHS R01 AI103055NIAID NIH HHS R01 AI106878NIAID NIH HHS R01 AI137127NIAID NIH HHS R01 AI137164NIAID NIH HHS R37 AI106878NIAID NIH HHS R56 AI106878NIAID NIH HHS T32 AI074492
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, BacterialAntibodies, MonoclonalBinding Sites, AntibodyImmunoglobulin AImmunoglobulin GImmunoglobulin IsotypesO AntigensVibrio cholerae O1Antibodies, BacterialAntibodies, MonoclonalImmunoglobulin AImmunoglobulin GImmunoglobulin IsotypesO Antigensimmunoglobulin isotypeOSP antibodyVibrio cholerae

Identifiers

PMID33879588
PMCPMC8092325
OpenAlexW3156041244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.