Evidence map›Paper›PMID 33879532›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2021

Independent and Joint Effects of Testosterone Replacement Therapy and Statins use on the Risk of Prostate Cancer Among White, Black, and Hispanic Men.

David S Lopez, Efstathia Polychronopoulou, Konstantinos K Tsilidis, Mohit Khera, L Joseph Su, Jay H Fowke, M K Peek, Yong-Fang Kuo, Kyriakos Markides, Steven Canfield

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

David S LopezDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, Texas. davlopez@utmb.edu.ORCID 0000-0002-2321-0372
Efstathia PolychronopoulouDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, Texas.
Konstantinos K TsilidisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Mohit KheraScott Department of Urology, Baylor College of Medicine, Houston, Texas.
L Joseph SuDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas.ORCID 0000-0002-4332-2363
Jay H FowkeDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.ORCID 0000-0003-3803-8162
M K PeekDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, Texas.
Yong-Fang KuoDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, Texas.ORCID 0000-0003-1927-0927
Kyriakos MarkidesDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, Texas.
Steven CanfieldDivision of Urology, UTHealth McGovern Medical School, Houston, Texas.
The University of Texas Medical Branch at Galveston · USBaylor College of Medicine · USThe University of Texas Health Science Center · USUniversity of Arkansas for Medical Sciences · USUniversity of Ioannina · GRUniversity of Tennessee Health Science Center · US

Funding

The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kyriakos S Markides, Fernando Riosmena · 2018 to 2026
$5.2M
NIA NIH HHS P30 AG059301
6 · The paper itself

Abstract

The associations of testosterone therapy (TTh) and statins use with prostate cancer remain conflicted. However, the joint effects of TTh and statins use on the incidence of prostate cancer, stage and grade at diagnosis, and prostate cancer-specific mortality (PCSM) have not been studied.We identified White (

Indexed as

AgedAged, 80 and overBlack or African AmericanFollow-Up StudiesHispanic or LatinoHormone Replacement TherapyHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIncidenceMaleMedicareNeoplasm GradingNeoplasm StagingProstatic NeoplasmsRisk AssessmentRisk FactorsHydroxymethylglutaryl-CoA Reductase InhibitorsTestosterone

Identifiers

PMID33879532
PMCPMC8260462
OpenAlexW3155274887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.