ArticleeLife2021
Tissue-specific modulation of gene expression in response to lowered insulin signalling in
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Remembrance of things past: Towards a life-course biology of aging.PLoS biology · 2026Article
- Lifespan-extending downregulation of insulin signalling reduces germline mutation load.bioRxiv : the preprint server for biology · 2025Article
- Lysosome heterogeneity and diversity mapped through its distinct cellular functions.Cellular and molecular life sciences : CMLS · 2025Review
- Dissecting metabolic regulation of behaviors and physiology during aging in Drosophila.Biogerontology · 2025Article
- Mitochondrial sirtuin 4 shapes the intestinal microbiota of Drosophila by controlling lysozyme expression.Animal microbiome · 2025Article
- Dissecting Metabolic Control of Behaviors and Physiology During Aging in Drosophila.Research square · 2025Article
- Optogenetic induction of mechanical muscle stress identifies myosin regulatory ubiquitin ligase NHL-1 in C. elegans.Nature communications · 2024Article
- What do we mean by "aging"? Questions and perspectives revealed by studies in Drosophila.Mechanisms of ageing and development · 2023Article
- Article
- Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy.Nature aging · 2022Article
- Quantification of tissue-specific protein translation in wholeCell reports methods · 2022Article
- Tissue-specific modulation of gene expression in response to lowered insulin signalling ineLife · 2021Article
- Sensory perception of rivals has trait-dependent effects on plasticity inBehavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
Reduced activity of the insulin/IGF signalling network increases health during ageing in multiple species. Diverse and tissue-specific mechanisms drive the health improvement. Here, we performed tissue-specific transcriptional and proteomic profiling of long-lived
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.