Evidence map›Paper›PMID 33879247›Full record

ArticleParasites & vectors2021

Co-infection of hepatitis E virus and Plasmodium falciparum malaria: A genuine risk in sub-Saharan Africa.

Syeda Sahra, Abdullah Jahangir, Qasim Zafar Iqbal, Neville Mobarakai, Allison Glaser, Ahmad Jahangir

Abstract readCase Reports
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Co-infection of hepatitis E virus,Frontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Syeda SahraStaten Island University Hospital, Staten Island, NY, 10305, USA. ssahra@northwell.edu.ORCID http://orcid.org/0000-0003-0119-3329
Abdullah JahangirStaten Island University Hospital, Staten Island, NY, 10305, USA.
Qasim Zafar IqbalStaten Island University Hospital, Staten Island, NY, 10305, USA.
Neville MobarakaiStaten Island University Hospital, Staten Island, NY, 10305, USA.
Allison GlaserStaten Island University Hospital, Staten Island, NY, 10305, USA.
Ahmad JahangirKing Edward Medical University, Lahore, 54000, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a high prevalence of malaria and viral hepatitis in South Africa. Co-infection with Plasmodium malaria (leading to cerebral malaria) and hepatitis E virus (HEV) is a rare phenomenon. CASE PRESENTATION: A 33-year-old African American male with no past medical history developed altered mental status on his return from Ivory Coast. His blood tests were significant for renal and liver failure and a high Plasmodium parasite burden of 33% on the blood smear. Interestingly, he also had a positive result for hepatitis E IgM. The patient was effectively treated with aggressive hydration and intravenous (IV) artesunate.

conclusionOur report is the first to our knowledge in the cerebral malaria literature on a patient with hepatitis E co-infection. This exciting case emphasizes the importance of considering all kinds of endemic infectious diseases when evaluating sick returning travelers presenting to the emergency department.

Indexed as

AdultCoinfectionHepatitis EHepatitis E virusHumansMalaria, CerebralMalaria, FalciparumMalePlasmodium falciparumRisk FactorsSouth AfricaCerebral malariaCOVID-19Hepatitis E virusHEVPlasmodium falciparum

Identifiers

PMID33879247
PMCPMC8056203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.