ReviewDiagnostic pathology2021
The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior.
Review in Diagnostic pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
118 citing papers in PubMed, 1 synthesis or guideline pooled it, 179 citations in OpenAlex.
- Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report.Frontiers in oral health · 2026Pooled it
- MRI of spermatic cord lesions: a practical pattern-based approach.Abdominal radiology (New York) · 2026Review
- Anterior Chest Wall Pilonidal Sinus Mimicking Recurrent Abscess: Diagnostic Pitfalls and Therapeutic Implications.Diagnostics (Basel, Switzerland) · 2026Article
- Construction and Characterization of Paired Patient-Derived Cell Models for Solitary Fibrous Tumors (SFTs).Cancers · 2026Article
- Primary Hepatic Solitary Fibrous Tumour: A Rare Mesenchymal Entity with Distinct Histopathologic and Molecular Features.Diagnostics (Basel, Switzerland) · 2026Article
- Review
- Article
- Article
- Clinicopathological characteristics and outcomes of 42 cases of ocular adnexal sarcoma.International ophthalmology · 2026Article
- Primary small intestine angiofibroma of soft tissue (AFST) with intussusception: an extremely rare case report and review of literature.BMC gastroenterology · 2026Review
- Article
- Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases.Diagnostic cytopathology · 2026Article
- Subcutaneous Solitary Fibrous Tumor in the Chin of a Young Adult: A Diagnostic Challenge.The American journal of case reports · 2026Article
- Primary orbital solitary fibrous tumor with an 18-year course of five recurrences and extensive sinonasal metastasis following eyeball enucleation: a case report.Frontiers in medicine · 2026Article
- Intraoperative vascular ligation uncovers the role of tumor vasculature in Doege-Potter syndrome: a case report.Frontiers in oncology · 2026Article
- Solitary fibrous tumor of the sublingual gland: a case report.Frontiers in oral health · 2026Article
- Solitary Fibrous Tumor With a 12-Year Recurrence Interval in a Female Patient: A Case Report.Cureus · 2026Article
- Solitary Fibrous Tumors of the Head and Neck: A Report of Two Cases and Review of the Literature.Cureus · 2026Article
- Pelvic solitary fibrous tumors: clinical manifestations, surgical management and long-term outcomes.Frontiers in oncology · 2026Article
- Solitary fibrous tumor: an updated review.Journal of pathology and translational medicine · 2026Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSolitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and exhibits a wide spectrum of histological features. MAIN BODY: Apart from diversity in morphological features seen even in conventional SFT, two histologic variants (fat-forming and giant cell-rich) are also recognized. In addition, a malignant form and dedifferentiation are well recognized. Owing to diverse histological features and involvement of diverse anatomic locations, SFT can mimic other soft tissue neoplasms of different lineages including schwannoma, spindle cell lipoma, dermatofibrosarcoma protuberans, liposarcoma, gastrointestinal stromal tumor (GIST), malignant peripheral nerve sheath tumor (MPNST), and synovial sarcoma. SFT is classified as an intermediate (rarely metastasizing) tumor according to World Health Organization Classification of Tumors of Soft tissue and Bone, 5th edition. The management and prognosis of SFT differs from its malignant mimics and correct diagnosis is therefore important. Although SFT expresses a distinct immunohistochemical (IHC) profile, the classic histomorphological and IHC profile is not seen in all cases and diagnosis can be challenging. NAB2-STAT6 gene fusion has recently emerged as a sensitive and specific molecular marker and its IHC surrogate marker signal transducer and activator of transcription 6 (STAT6) has also shown significant sensitivity and specificity. However, few recent studies have reported STAT6 expression in other soft tissue neoplasms.
conclusionThis review will focus on describing the diversity of histological features of SFT, differential diagnoses and discussing the features helpful in distinguishing SFT from its histological mimics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.