Evidence map›Paper›PMID 33879133›Full record

ArticleBMC musculoskeletal disorders2021

Standardized artificially created stable pertrochanteric femur fractures present more homogenous results compared to osteotomies for orthopaedic implant testing.

J F Schader, I Zderic, D Gehweiler, J Dauwe, K Mys, C Danker, Y P Acklin, C Sommer, B Gueorguiev, K Stoffel

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

J F SchaderAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland. janaschader@gmail.com.
I ZdericAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
D GehweilerAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
J DauweAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
K MysAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
C DankerAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
Y P AcklinUniversity Hospital Basel, Basel, Switzerland.
C SommerDepartment of Surgery, Cantonal Hospital Graubuenden, Chur, Switzerland.
B GueorguievAO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos Platz, Switzerland.
K StoffelUniversity of Basel, Basel, Switzerland.
AO Foundation · CHUniversity Hospital of Basel · CHUniversitair Ziekenhuis Leuven · BEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith regard to biomechanical testing of orthopaedic implants, there is no consensus on whether artificial creation of standardized bone fractures or their simulation by means of osteotomies result in more realistic outcomes. Therefore, the aim of this study was to artificially create and analyze in an appropriate setting the biomechanical behavior of standardized stable pertrochanteric fractures versus their simulation via osteotomizing.

methodsEight pairs of fresh-frozen human cadaveric femora aged 72.7 ± 14.9 years (range 48-89 years) were assigned in paired fashion to two study groups. In Group 1, stable pertrochanteric fractures AO/OTA 31-A1 were artificially created via constant force application on the anterior cortex of the femur through a blunt guillotine blade. The same fracture type was simulated in Group 2 by means of osteotomies. All femora were implanted with a dynamic hip screw and biomechanically tested in 20° adduction under progressively increasing physiologic cyclic axial loading at 2 Hz, starting at 500 N and increasing at a rate of 0.1 N/cycle. Femoral head fragment movements with respect to the shaft were monitored by means of optical motion tracking.

resultsCycles/failure load at 15° varus deformation, 10 mm leg shortening and 15° femoral head rotation around neck axis were 11324 ± 848/1632.4 ± 584.8 N, 11052 ± 1573/1605.2 ± 657.3 N and 11849 ± 1120/1684.9 ± 612.0 N in Group 1, and 10971 ± 2019/1597.1 ± 701.9 N, 10681 ± 1868/1568.1 ± 686.8 N and 10017 ± 4081/1501.7 ± 908.1 N in Group 2, respectively, with no significant differences between the two groups, p ≥ 0.233.

conclusionFrom a biomechanical perspective, by resulting in more consistent outcomes under dynamic loading, standardized artificial stable pertrochanteric femur fracture creation may be more suitable for orthopaedic implant testing compared to osteotomizing the bone.

Indexed as

OrthopedicsAgedAged, 80 and overBiomechanical PhenomenaFemurFracture Fixation, InternalHumansMiddle AgedOsteotomyFracture biomechanicsFracture line analysisFracture modelFracture standardizationOsteotomyProximal femur fractureStable pertrochanteric fracture

Identifiers

PMID33879133
PMCPMC8058974
OpenAlexW3156121451

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.