Evidence map›Paper›PMID 33879083›Full record

ArticleBMC infectious diseases2021

The causal relationship between O2:K7:H6 extra-intestinal pathogenic Escherichia coli (ExPEC) and native valve endocarditis: a case report.

Marie-Françoise Leonard, Hector Rodriguez-Villalobos, Nadia Boisen, Flemming Scheutz, Pierre-François Laterre, Philippe Hantson

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Infective endocarditis caused byThe Journal of international medical research · 2025
    Article
  2. Article
  3. Extraintestinal PathogenicMicrobiology spectrum · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marie-Françoise LeonardLaboratoire Synlab, 4020, Liège, Belgium.
Hector Rodriguez-VillalobosDepartment of Microbiology, Cliniques universitaires St-Luc, Université catholique de Louvain, Brussels, Belgium.
Nadia BoisenDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, The International Centre for Reference and Research on Escherichia and Klebsiella, Copenhagen, Denmark.
Flemming ScheutzDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, The International Centre for Reference and Research on Escherichia and Klebsiella, Copenhagen, Denmark.
Pierre-François LaterreDepartment of Intensive Care, Cliniques universitaires St-Luc, Université catholique de Louvain, Brussels, Belgium.
Philippe HantsonDepartment of Intensive Care, Cliniques universitaires St-Luc, Université catholique de Louvain, Brussels, Belgium. philippe.hantson@uclouvain.be.ORCID http://orcid.org/0000-0003-4409-3352
Cliniques Universitaires Saint-Luc · BEStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNative valves infective endocarditis due to Escherichia coli is still a rare disease and a particular virulence of some E.coli isolate may be suspected. CASE PRESENTATION: A 79-year-old woman presented during the post-operative period of an orthopedic surgery a urinary tract infection following obstructive ureteral lithiasis. E. coli was isolated from a pure culture of urine and blood sampled simultaneously. After evidence of sustained E.coli septicemia, further investigations revealed acute cholecystitis with the same micro-organism in biliary drainage and a native valve mitral endocarditis. E.coli was identified as O2:K7:H6, phylogenetic group B2, ST141, and presented several putative and proven virulence genes. The present isolate can be classified as both extra-intestinal pathogenic E.coli (ExPEC

conclusionsThe relationship between the virulent factors present in ExPEC strains and some serotypes of E. coli that could facilitate the adherence to cardiac valves warrants further investigation.

Indexed as

AgedAnimalsEndocarditisExtraintestinal Pathogenic Escherichia coliFemaleHumansOrthopedic ProceduresPhylogenyPostoperative PeriodUrinary Tract InfectionsUrolithiasisVirulenceCase reportEndocarditisEscherichia coliNative mitral valveUrinary tract infection - virulence factors

Identifiers

PMID33879083
PMCPMC8056695
OpenAlexW3153427320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.