Evidence map›Paper›PMID 33879069›Full record

ArticleBMC pregnancy and childbirth2021

Antenatal depressive symptoms and adverse perinatal outcomes.

Despina Pampaka, Stefania I Papatheodorou, Mohammad AlSeaidan, Rihab Al Wotayan, Rosalind J Wright, Julie E Buring, Douglas W Dockery, Costas A Christophi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Despina PampakaCyprus International Institute for Environmental and Public Health, Cyprus University of Technology, 95 Eirinis Street, 3041, Limassol, Cyprus.ORCID https://orcid.org/0000-0001-8594-6054
Stefania I PapatheodorouDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID https://orcid.org/0000-0002-9451-9094
Mohammad AlSeaidanDasman Diabetes Institute, Kuwait, Kuwait.ORCID https://orcid.org/0000-0002-6016-9102
Rihab Al WotayanPrimary Health Care, Ministry of Health, Kuwait, Kuwait.
Rosalind J WrightDepartment of Pediatrics & Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID https://orcid.org/0000-0002-4262-2807
Julie E BuringDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Douglas W DockeryDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6052-4880
Costas A ChristophiCyprus International Institute for Environmental and Public Health, Cyprus University of Technology, 95 Eirinis Street, 3041, Limassol, Cyprus. costas.christophi@cut.ac.cy.
Harvard University · USBrigham and Women's Hospital · USCyprus University of Technology · CYDasman Diabetes Institute · KWIcahn School of Medicine at Mount Sinai · USMinistry of Health · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association of antenatal depression with adverse pregnancy, birth, and postnatal outcomes has been an item of scientific interest over the last decades. However, the evidence that exists is controversial or limited. We previously found that one in five women in Kuwait experience antenatal depressive symptoms. Therefore, the aim of this study was to examine whether antenatal depressive symptoms are associated with preterm birth (PTB), small for gestational age (SGA), or large for gestational age (LGA) babies in this population.

methodsThis was a secondary analysis based on data collected in the Transgenerational Assessment of Children's Environmental Risk (TRACER) Study that was conducted in Kuwait. Logistic regression analysis was used to examine whether antenatal depressive symptoms assessed using the Edinburgh Depression Scale (EDS) were associated with preterm birth, small for gestational age, and large for gestational age babies.

resultsA total of 1694 women had complete information about the outcomes of interest. Women with depressive symptoms in pregnancy had increased, albeit non-significant, odds of having PTB (OR = 1.41; 95%CI: 0.81, 2.45), SGA babies (OR = 1.26; 0.80, 1.98), or LGA babies (OR = 1.27; 0.90, 1.79). Antenatal depressive symptoms had similar increased odds for the three outcomes even after adjusting for several covariates though none of these reached statistical significance.

conclusionsIn the present study, the depressive symptoms in pregnancy did not predict adverse birth outcomes, such as PTB, SGA, and LGA, which adds to the currently non-conclusive literature. However, further research is needed to examine these associations, as the available evidence is quite limited.

Indexed as

AdultCohort StudiesDepressionFemaleHumansInfant, NewbornInfant, Small for Gestational AgeKuwaitPregnancyPregnancy ComplicationsPremature BirthProspective StudiesYoung AdultAdverse perinatal outcomesAntenatal depressive symptomsKuwaitLarge for gestational agePreterm birthSmall for gestational age

Identifiers

PMID33879069
PMCPMC8059279
OpenAlexW3153738094

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.