Evidence map›Paper›PMID 33879059›Full record

ArticleThe journal of physiological sciences : JPS2021

Open-loop analysis on sympathetically mediated arterial pressure and urine output responses in spontaneously hypertensive rats: effect of renal denervation.

Toru Kawada, Takuya Nishikawa, Satoru Suehara, Satoshi Sawada, Tetsuo Tanaka, Minako Uenohara, Hiromi Yamamoto, Masaru Sugimachi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physiological sciences : JPS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Effects of bilateral renal denervation on open-loop baroreflex function and urine excretion in spontaneously hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Toru KawadaDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan. torukawa@ncvc.go.jp.ORCID http://orcid.org/0000-0002-4429-1802
Takuya NishikawaDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan.
Satoru SueharaCorporate R&D Center, Terumo Corporation, Kanagawa, 259-0151, Japan.
Satoshi SawadaCorporate R&D Center, Terumo Corporation, Kanagawa, 259-0151, Japan.
Tetsuo TanakaCorporate R&D Center, Terumo Corporation, Kanagawa, 259-0151, Japan.
Minako UenoharaCorporate R&D Center, Terumo Corporation, Kanagawa, 259-0151, Japan.
Hiromi YamamotoDepartment of Cardiology, Kurashiki Central Hospital, Ohara HealthCare Foundation, Okayama, 710-8602, Japan.
Masaru SugimachiDepartment of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan.
Terumo (Japan) · JPNational Cerebral and Cardiovascular Center · JPKurashiki Central Hospital · JP

Funding

Japan Society for the Promotion of Science 18K06451Japan Society for the Promotion of Science 18K10695Japan Society for the Promotion of Science 20K20622Salt Science Research Foundation 1921, 2029
6 · The paper itself

Abstract

Primary acute sympathetic activation (PASA) causes a subsequent arterial pressure (AP) elevation. In this case, an antidiuretic effect via the renal innervation and pressure diuresis can act antagonistically on the kidneys. We examined the effect of PASA on urine output in spontaneously hypertensive rats (SHR) 4-7 days after unilateral renal denervation (RDN) (n = 9). The slope of the plot of urine flow versus AP was positive (0.120 ± 0.031 μL min

Indexed as

Arterial PressureUrodynamicsAnimalsCreatinineKidneyMaleRatsRats, Inbred SHRSodiumSympathectomyCreatinineSodiumArterial pressureEquilibrium diagramOpen-loop analysisPressure diuresisSympathetic nerve activity

Identifiers

PMID33879059
PMCPMC10717997
OpenAlexW3154698843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.