Evidence map›Paper›PMID 33878961›Full record

Observational studyTherapeutic advances in respiratory disease

Three-month outcomes of recovered COVID-19 patients: prospective observational study.

Jie Cao, Xueying Zheng, Wei Wei, Xinmin Chu, Xianmeng Chen, Ying Wang, Qiqi Liu, Sihui Luo, Jianping Weng, Xiaowen Hu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
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  3. Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jie CaoDepartment of Pulmonary and Critical Care Medicine, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xueying ZhengDepartment of Endocrine, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Wei WeiDepartment of Radiology, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xinmin ChuDepartment of Clinical Laboratory, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xianmeng ChenDepartment of Pulmonary and Critical Care Medicine, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Ying WangDepartment of Radiology, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Qiqi LiuDepartment of Rehabilitation (now at Department of Rehabilitation, the Second People's Hospital of Hefei), The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Sihui LuoDepartment of Endocrine, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Jianping WengDepartment of Endocrine, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Xiaowen HuDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Room 302, Building 9, 17 Lujiang Road, Luyang District, Hefei, Anhui, 230001, China.ORCID 0000-0002-3727-6049
University of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsA novel coronavirus SARS-CoV-2 has resulted in an ongoing global pandemic of Coronavirus disease 2019 (COVID-19). However, the outcomes of recovered patients have not been well defined.

methodsThis is a prospective observational follow-up study of survivors with COVID-19 from a designated tertiary center in Hefei, China. We examined chest computed tomography (CT) scanning, pulmonary function, 6-min walk distance (6MWD), and 36 item Short Form General Health Survey (SF-36).

resultsAmong 81 enrolled patients, 62 (77%) patients and 61 (75%) patients, respectively, completed 1-month and 3-month follow-ups. Abnormal CT findings were still present in 73% of patients at 1 month and 54% at 3 months, whereas chest CT scan scores improved progressively at 1-month (5.0 ± 5.1) and 3-month follow up (3.0 ± 4.5) compared with that during hospitalization (11 ± 6.8). Mild restrictive pulmonary impairment was detected in 11% and 10% of patients at 1-month and 3-month follow up, respectively. The 6MWD was 523 ± 77 m in male patients and 484 ± 58 m in female patients, which was significantly lower than in healthy controls (606 ± 68 m, 568 ± 78 m,

conclusionsAt 3 months, chest CT abnormalities were present in one half of COVID-19 survivors and worse chest CT scores were independently associated with older age and steroid administration during hospitalization. Residual pulmonary function impairments were modest, whereas exercise capacity and SF-36 scores were significantly lower than the general population. Support program and further follow-up evaluations may be needed.

Indexed as

SARS-CoV-2AdultAge FactorsCOVID-19FemaleHumansLungMaleMiddle AgedProspective StudiesRadiography, ThoracicTime FactorsTomography, X-Ray ComputedWalking SpeedCoronavirus disease 2019functional capacitylung functionSARS-CoV-2

Identifiers

PMID33878961
PMCPMC8064514
OpenAlexW3156094660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.