ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2021
"HIFU Beam:" A Simulator for Predicting Axially Symmetric Nonlinear Acoustic Fields Generated by Focused Transducers in a Layered Medium.
Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- All-optical generation and predictive modeling of focused pressure waves using Bessel beam shaping and a nanocomposite thin film.Photoacoustics · 2026Article
- A systematic comparison of cavitation regimes and histotripsy efficiency across pulse duration and repetition rate in a fibrous tissue mimicking phantom.Research square · 2026Article
- High-intensity focused ultrasound (HIFU) modeling: in vitro validation and integration into patient-specific planning tool.Scientific reports · 2026Article
- Monitoring Fractionation in Elastic Tissues Using High Frame-Rate Doppler Ultrasound.Ultrasound in medicine & biology · 2025Article
- Simulation Study on the Effect of HIFU Irradiation Frequency and Duty Cycle Combination Parameter Optimization on Thermal Lesion of Biological Tissue.Journal of biomedical physics & engineering · 2025Article
- Fabrication of poly (ɛ-caprolactone) 3D scaffolds with controllable porosity using ultrasound.Scientific reports · 2025Article
- Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Review
- Study on the Effect of Lesion Volume and Focal Temperature Caused by HIFU Combined with Different Concentrations and Volumes of Ethanol on Porcine Liver.Journal of biomedical physics & engineering · 2025Article
- Histotripsy-Induced Bactericidal Activity Correlates to Size of Cavitation Cloud In Vitro.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Article
- Histotripsy: A Method for Mechanical Tissue Ablation with Ultrasound.Annual review of biomedical engineering · 2024Review
- Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing.Science (New York, N.Y.) · 2023Article
- Pilot ex vivo study on non-thermal ablation of human prostate adenocarcinoma tissue using boiling histotripsy.Ultrasonics · 2023Article
- Comparative Characterization of Nonlinear Ultrasound Fields Generated by Sonalleve V1 and V2 MR-HIFU Systems.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Dual-frequency boiling histotripsy in an ex vivo bovine tendinopathy model.The Journal of the Acoustical Society of America · 2023Article
- Histotripsy Bubble Dynamics in Elastic, Anisotropic Tissue-Mimicking Phantoms.Ultrasound in medicine & biology · 2023Article
- High intensity focused ultrasound atomization and erosion in healthy and tendinopathic tendons.Physics in medicine and biology · 2023Article
- Initial Assessment of Boiling Histotripsy for Mechanical Ablation of Ex Vivo Human Prostate Tissue.Ultrasound in medicine & biology · 2023Article
- Quantitative Assessment of Boiling Histotripsy Progression Based on Color Doppler Measurements.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Mechanical damage thresholds for hematomas near gas-containing bodies in pulsed HIFU fields.Physics in medicine and biology · 2022Article
- Ultrasound-Responsive Hydrogels for On-Demand Protein Release.ACS applied bio materials · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
"HIFU beam" is a freely available software tool that comprises a MATLAB toolbox combined with a user-friendly interface and binary executable compiled from FORTRAN source code (HIFU beam. (2021). Available: http://limu.msu.ru/node/3555?language=en). It is designed for simulating high-intensity focused ultrasound (HIFU) fields generated by single-element transducers and annular arrays with propagation in flat-layered media that mimic biological tissues. Numerical models incorporated in the simulator include evolution-type equations, either the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation or one-way Westervelt equation, for radially symmetric ultrasound beams in homogeneous and layered media with thermoviscous or power-law acoustic absorption. The software uses shock-capturing methods that allow for simulating strongly nonlinear acoustic fields with high-amplitude shocks. In this article, a general description of the software is given along with three representative simulation cases of ultrasound transducers and focusing conditions typical for therapeutic applications. The examples illustrate major nonlinear wave effects in HIFU fields including shock formation. Two examples simulate propagation in water, involving a single-element source (1-MHz frequency, 100-mm diameter, 90-mm radius of curvature) and a 16-element annular array (3-MHz frequency, 48-mm diameter, and 35-mm radius of curvature). The third example mimics the scenario of a HIFU treatment in a "water-muscle-kidney" layered medium using a source typical for abdominal HIFU applications (1.2-MHz frequency, 120-mm diameter, and radius of curvature). Linear, quasi-linear, and shock-wave exposure protocols are considered. It is intended that "HIFU beam" can be useful in teaching nonlinear acoustics; designing and characterizing high-power transducers; and developing exposure protocols for a wide range of therapeutic applications such as shock-based HIFU, boiling histotripsy, drug delivery, immunotherapy, and others.
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