ReviewNeurology and therapy2021
Patient and Provider Insights into the Impact of Multiple Sclerosis on Mental Health: A Narrative Review.
Review in Neurology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- National and Subnational Models of Care That Support Primary Health Care: A Mixed-Methods Study.The International journal of health planning and management · 2026Article
- Psychological Burden in Relapsing-Remitting Multiple Sclerosis: Sociodemographic and Clinical Determinants of Persistent Anxiety and Depression over a Six-Month Follow-Up.Nursing reports (Pavia, Italy) · 2026Article
- Predicting Quality of Life in Relapsing-Remitting Multiple Sclerosis: Clinical Burden Meets Emotional Balance in Early Disease.Neurology international · 2025Article
- Disordered Eating Behaviors in Individuals With Physical Disabilities: A Narrative Review.American journal of lifestyle medicine · 2025Review
- Development and validation of the antecedents affecting coping questionnaire in patients with multiple sclerosis.BMC neurology · 2025Article
- Understanding Depression in People Living with Multiple Sclerosis: A Narrative Review of Recent Literature.Neurology and therapy · 2025Review
- Exploring the Therapeutic Role of Coach-Guided Videoconferencing Expressive Writing in Multiple Sclerosis: A Qualitative Study.Healthcare (Basel, Switzerland) · 2025Article
- Impact of Depression, Fatigue, and Pain on Quality of Life in Slovak Multiple Sclerosis Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- The effects of Leventhal's self-regulation model-based educational intervention on stress, anxiety, and depression in women with multiple sclerosis: a randomized educational trial.Frontiers in neurology · 2025Article
- Navigating the Unknown: A Qualitative Exploration of the Lived Experiences of People With Multiple Sclerosis During Pregnancy.International journal of MS care · 2025Article
- Multiple sclerosis and self-alienation: a study based on self and others representations.BMC psychology · 2024Article
- Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study.Journal of personalized medicine · 2024Article
- Alexithymia and attachment on mental health of people with multiple sclerosis: The mediating role of perceived social support and loneliness.Journal of education and health promotion · 2024Article
- Long-term consequences of COVID-19 on mental health and the impact of a physically active lifestyle: a narrative review.Annals of general psychiatry · 2023Review
- Neuroimmune, clinical and treatment challenges in multiple sclerosis-related psychoses.World journal of psychiatry · 2023Review
- Understanding the Effect of Multiple Sclerosis on General and Dimensions of Mental Health.Journal of clinical medicine · 2022Article
- High-Efficacy Therapies for Treatment-Naïve Individuals with Relapsing-Remitting Multiple Sclerosis.CNS drugs · 2022Review
- PECAM-1 Is Down-Regulated in γδT Cells during Remission, but Up-Regulated in Relapse of Multiple Sclerosis.Journal of clinical medicine · 2022Article
- Telemedicine as a strategic intervention for cognitive rehabilitation in MS patients during COVID-19.Acta neurologica Belgica · 2022Review
- A meta-review of psychological resilience during COVID-19.Npj mental health research · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple sclerosis (MS) is a chronic disease in which the immune system attacks the central nervous system, causing inflammation and neurodegeneration. People living with MS may experience a variety of symptoms as a consequence of this process, including many "invisible" symptoms that are internally manifested and not seen by others. Of the invisible symptoms of MS, which we have reviewed in a companion article, mood and mental health disorders are of particular concern due to their high prevalence and significant impact on patient quality of life. In this review, we showcase the experiences of patient authors alongside perspectives from healthcare provider authors as we promote awareness of the common mental health conditions faced by those living with MS, such as depression, anxiety, adjustment disorder, bipolar disorder, psychosis, and suicidal ideation. Many of these conditions stem in part from the increased stress levels and the many uncertainties that come with managing life with MS, which have been exacerbated by the environment created by the coronavirus disease 2019 (COVID-19) pandemic. A patient-centered interdisciplinary approach, routine screening for mental health changes, and referral to specialists when needed can normalize discussions of mental health and increase the likelihood that people living with MS will receive the support and care they need. Management techniques such as robust social support, cognitive behavioral therapy, mindfulness-based interventions, and/or pharmacotherapy may be implemented to build resilience and promote healthy coping strategies. Increasingly, patients have access to telehealth options as well as digital apps for mental health management. Taken together, these approaches form an integrative care model in which people living with MS benefit from the care of medical professionals, a variety of support networks/resources, and self-management techniques for optimal mental health care.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.