Evidence map›Paper›PMID 33877452›Full record

ArticleSurgery today2021

Thoracoscopic repair of congenital diaphragmatic hernia in neonates: findings of a multicenter study in Japan.

Manabu Okawada, Satoko Ohfuji, Masaya Yamoto, Naoto Urushihara, Keita Terui, Kouji Nagata, Tomoaki Taguchi, Masahiro Hayakawa, Shoichirou Amari, Kouji Masumoto and 12 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022
    Review
  13. Unsolved problems in CDH follow-up.Frontiers in pediatrics · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Manabu OkawadaDepartment of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4997-4485
Satoko OhfujiDepartment of Public Health, Osaka City University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Masaya YamotoDepartment of Pediatric Surgery, Shizuoka Children's Hospital, Shizuoka, Japan.
Naoto UrushiharaDepartment of Pediatric Surgery, Shizuoka Children's Hospital, Shizuoka, Japan.
Keita TeruiDepartment of Pediatric Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kouji NagataDepartment of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tomoaki TaguchiDepartment of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masahiro HayakawaCenter for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
Shoichirou AmariDivision of Neonatology, National Center for Child Health and Development, Tokyo, Japan.
Kouji MasumotoDepartment of Pediatric Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Tadaharu OkazakiDepartment of Pediatric Surgery, Juntendo University Urayasu Hospital, Chiba, Japan.
Noboru InamuraDepartment of Pediatrics, Faculty of Medicine, Kinki University, Osaka-Sayama, Japan.
Katsuaki ToyoshimaDepartments of Neonatology, Kanagawa Children's Medical Center, Yokohama, Japan.
Mikihiro InoueDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Taizo FurukawaDepartment of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Akiko YokoiDepartment of Pediatric Surgery, Kobe Children's Hospital, Hyogo, Japan.
Yutaka KanamoriDivision of surgery, National Center for Child Health and Development, Tokyo, Japan.
Noriaki UsuiDepartment of Pediatric Surgery, Osaka Women's and Children's Hospital, Izumi, Japan.
Yuko TazukeDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Ryuta SakaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Hiroomi OkuyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. okuyama@pedsurg.med.osaka-u.ac.jp.
Japanese Congenital Diaphragmatic Hernia Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the efficacy of thoracoscopic repair (TR) with that of open repair (OR) for neonatal congenital diaphragmatic hernia (CDH).

methodsThe subjects of this multicenter retrospective cohort study were 524 infants with left-sided isolated CDH, diagnosed prenatally, and treated at one of 15 participating hospitals in Japan between 2006 and 2018. The outcomes of infants who underwent TR and those who underwent OR were compared, applying propensity score matching.

resultsDuring the study period, 57 infants underwent TR and 467 underwent OR. Ten of the infants who underwent TR required conversion to OR for technical difficulties and these patients were excluded from the analysis. The survival rate at 180 days was similar in both groups (TR 98%; OR 93%). Recurrence developed after TR in 3 patients and after OR in 15 patients (TR 7%, OR 3%, p = 0.40). The propensity score was calculated using the following factors related to relevance of the surgical procedure: prematurity (p = 0.1), liver up (p < 0.01), stomach position (p < 0.01), and RL shunt (p = 0.045). After propensity score matching, the multivariate analysis adjusted for severity classification and age at surgical treatment revealed a significantly shorter hospital stay (odds ratio 0.50) and a lower incidence of chronic lung disease (odds ratio 0.39) in the TR group than in the OR group.

conclusionsTR can be performed safely for selected CDH neonates with potentially better outcomes than OR.

Indexed as

Multicenter Studies as TopicAge FactorsFemaleHernias, Diaphragmatic, CongenitalHerniorrhaphyHumansInfant, NewbornJapanLength of StayMalePropensity ScoreRetrospective StudiesSeverity of Illness IndexSurvival RateThoracoscopyTreatment OutcomeCongenital diaphragmatic hernia (CDH)Open repairThoracoscopic repair

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.