SynthesisInternational journal of colorectal disease2021
Prophylactic mesh placement at index permanent end colostomy creation to prevent parastomal hernia-an updated meta-analysis.
Synthesis in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Pooled it
- Conflict resolution of the beams: CT vs. MRI in recurrent hernia detection: a systematic review and meta-analysis of mesh visualization and other outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Use of prophylactic mesh to prevent parastomal hernia formation: a systematic review, meta-analysis and network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Umbrella review of systematic reviews on the efficacy and safety of using mesh in the prevention of parastomal hernias.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- A systematic review of the association between parastomal hernia and sarcopenia.International journal of colorectal disease · 2023Pooled it
- Effectiveness of prophylactic Sugarbaker mesh during laparoscopic abdominoperineal resection: a cohort study with 4-year follow-up.Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- Development and validation of a prognostic model for the occurrence of parastomal hernia in patients undergoing permanent colostomy based on various computed tomography indices.Surgical endoscopy · 2026Article
- Prophylactic Mesh in Parastomal Hernia Prevention: Current Evidence.Journal of abdominal wall surgery : JAWS · 2025Review
- Parastomal hernia prevention with an intraperitoneal prophylactic 3D-funnel mesh: review of the technique and middle-term results.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- How often is prophylactic parastomal mesh placement performed after rectal resection without sphincter preservation? An analysis of German nationwide hospital discharge data among 41,697 patients.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Absorbable mesh in a contaminated field: hernia repair outcomes.Updates in surgery · 2023Article
- Use of prophylactic stoma mesh is a risk factor for developing rectus abdominis muscle atrophy.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDebate persists regarding the efficacy of prophylactic mesh insertion (PMI) at index permanent stoma creation to reduce the rate of parastomal hernia (PSH). This meta-analysis aimed to appraise all the latest evidence from newly published randomized controlled trials (RCTs) on PMI for PSH prevention.
methodsPubMed, EMBASE, and Cochrane databases were searched for relevant articles from inception until November 2020. All RCTs that reported on PMI at end colostomy creation with ≥ 12 months follow-up were included. The primary objective was the rate of clinical and radiological PSH while secondary objectives included number of PSH requiring repair and stoma (or mesh)-related complications. Random effects models were used to calculate pooled effect size estimates. Sensitivity analyses were also performed.
resultsEleven RCTs were included capturing 1097 patients. The mean (SD) age was 67.9 (±9.4) years. On random effects analysis, prophylactic mesh appeared to reduce the rate of both clinical (OR = 0.27, 95% CI = 0.12 to 0.61, p = 0.002) and radiological (OR = 0.39, 95% CI = 0.24 to 0.65, p = 0.0002) PSH. However, there was no difference in number of PSH requiring repair or stoma-related complications. On sensitivity analysis, when focusing on low-risk of bias studies, the benefit of prophylactic mesh in the retrorectus space was lost for both clinical (OR = 0.97, 95% CI = 0.62 to 1.51, p = 0.89) and radiological PSH (OR = 0.74, 95% CI = 0.46 to 1.18, p = 0.20).
conclusionPMI may reduce the rate of subsequent PSH. However, further studies are required to confirm these findings and to establish the optimal mesh position and shape before definite recommendations can be made.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.