Evidence map›Paper›PMID 33877411›Full record

ArticleSurgical endoscopy2022

Laparoscopic gastrectomy for stage II and III advanced gastric cancer: long‑term follow‑up data from a Western multicenter retrospective study.

Umberto Bracale, Giovanni Merola, Giusto Pignata, Jacopo Andreuccetti, Pasquale Dolce, Luigi Boni, Elisa Cassinotti, Stefano Olmi, Matteo Uccelli, Monica Gualtierotti and 11 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Open versus laparoscopic gastrectomy for advanced gastric cancer: a propensity score matching analysis of survival in a western population-on behalf of the Italian Research Group for Gastric Cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
    Article
  5. Article
  6. Review
  7. Minimally invasive surgery in advanced gastric cancer.Annals of gastroenterological surgery · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 2 countries.

Umberto BracaleDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy. umbertobracale@gmail.com.ORCID 0000-0002-9868-0889
Giovanni MerolaDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy.
Giusto PignataDepartment of General Surgery II, Spedali Civili of Brescia, Brescia, Italy.
Jacopo AndreuccettiDepartment of General and Mininvasive Surgery, San Camillo Hospital of Trento, Trento, Italy.
Pasquale DolceDepartment of Public Health, Federico II University of Naples, Naples, Italy.
Luigi BoniDepartment of Surgery, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Elisa CassinottiDepartment of Surgery, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Stefano OlmiDepartment of General and Oncologic Surgery, Centre of Advanced Laparoscopic Surgery, Centre of Bariatric Surgery, San Marco Hospital GSD, Zingonia, BG, Italy.
Matteo UccelliDepartment of General and Oncologic Surgery, Centre of Advanced Laparoscopic Surgery, Centre of Bariatric Surgery, San Marco Hospital GSD, Zingonia, BG, Italy.
Monica GualtierottiDepartment of Minimally Invasive Oncologic Surgery, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Giovanni FerrariDepartment of Minimally Invasive Oncologic Surgery, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Paolo De MartiniDepartment of Minimally Invasive Oncologic Surgery, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Miloš BjelovićDepartment for Minimally Invasive Upper Digestive Surgery, Hospital for Digestive Surgery, Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade, Serbia.
Dragan GunjićDepartment for Minimally Invasive Upper Digestive Surgery, Hospital for Digestive Surgery, Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade, Serbia.
Vania SilvestriDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy.
Emanuele PontecorviDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy.
Roberto PeltriniDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy.
Felice PirozziDepartment of General Surgery, Santa Maria Delle Grazie Hospital, Pozzuoli, NA, Italy.
Diego CuccurulloDepartment of General, Mini-Invasive and Robotic Surgery, Monaldi Hospital, Naples, NA, Italy.
Antonio SciutoDepartment of General Surgery, Santa Maria Delle Grazie Hospital, Pozzuoli, NA, Italy.
Francesco CorcioneDepartment of General Surgery and Specialty, School of Medicine University, Federico II of Naples, Naples, Italy.
University of Naples Federico II · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITOspedale Santa Maria · ITUniversity of Belgrade · RSUniversity of Milan · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITFederico II University Hospital · ITOspedale Monaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere has been an increasing interest for the laparoscopic treatment of early gastric cancer, especially among Eastern surgeons. However, the oncological effectiveness of Laparoscopic Gastrectomy (LG) for Advanced Gastric Cancer (AGC) remains a subject of debate, especially in Western countries where limited reports have been published. The aim of this paper is to retrospectively analyze short- and long-term results of LG for AGC in a real-life Western practice. MATERIALS AND

methodsAll consecutive cases of LG with D2 lymphadenectomy for AGC performed from January 2005 to December 2019 at seven different surgical departments were analyzed retrospectively. The primary outcome was diseases-free survival (DFS). Secondary outcomes were overall survival (OS), number of retrieved lymph nodes, postoperative morbidity and conversion rate.

resultsA total of 366 patients with stage II and III AGC underwent either total or subtotal LG. The mean number of harvested lymph nodes was 25 ± 14. The mean hospital stay was 13 ± 10 days and overall postoperative morbidity rate 27.32%, with severe complications (grade ≥ III) accounting for 9.29%. The median follow-up was 36 ± 16 months during which 90 deaths occurred, all due to disease progression. The DFS and OS probability was equal to 0.85 (95% CI 0.81-0.89) and 0.94 (95% CI 0.92-0.97) at 1 year, 0.62 (95% CI 0.55-0.69) and 0.63 (95% CI 0.56-0.71) at 5 years, respectively.

conclusionOur study has led us to conclude that LG for AGC is feasible and safe in the general practice of Western institutions when performed by trained surgeons.

Indexed as

LaparoscopyStomach NeoplasmsTesticular NeoplasmsFollow-Up StudiesGastrectomyHumansLymph Node ExcisionMaleRetrospective StudiesTreatment OutcomeAdvanced gastric cancerLaparoscopic gastrectomyLaparoscopyMalignancyStomach

Identifiers

PMID33877411
PMCPMC8921054
OpenAlexW3156551737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.