Evidence map›Paper›PMID 33877398›Full record

ReviewCurrent genetics2021

A snapshot of the λ T4rII exclusion (Rex) phenotype in Escherichia coli.

Shirley Wong, Hibah Alattas, Roderick A Slavcev

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Phages use contingency loci as a bet-hedging strategy.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Disarm The Bacteria: What Temperate Phages Can Do.Current issues in molecular biology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shirley Wong *School of Pharmacy, University of Waterloo, ON, N2L 3G1, Canada.
Hibah Alattas *School of Pharmacy, University of Waterloo, ON, N2L 3G1, Canada. hibah.alattas@uwaterloo.ca.ORCID http://orcid.org/0000-0001-6961-3022
Roderick A SlavcevSchool of Pharmacy, University of Waterloo, ON, N2L 3G1, Canada.
University of Waterloo · CA

Funding

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada 391457
6 · The paper itself

Abstract

The lambda (λ) T4rII exclusion (Rex) phenotype is defined as the inability of T4rII to propagate in Escherichia coli lysogenized by bacteriophage λ. The Rex system requires the presence of two lambda immunity genes, rexA and rexB, to exclude T4 (rIIA-rIIB) from plating on a lawn of E. coli λ lysogens. The onset of the Rex phenotype by T4rII infection imparts a harsh cellular environment that prevents T4rII superinfection while killing the majority of the cell population. Since the discovery of this powerful exclusion system in 1955 by Seymour Benzer, few mechanistic models have been proposed to explain the process of Rex activation and the physiological manifestations associated with Rex onset. For the first time, key host proteins have recently been linked to Rex, including σ

Indexed as

Bacteriophage lambdaBacteriophage T4Escherichia coliMutationPhenotypeViral Nonstructural ProteinsViral ProteinsRexA protein, Bacteriophage lambdarexB protein, Bacteriophage lambdaViral Nonstructural ProteinsViral ProteinsBacteriophage lambdaBacteriophage T4rIIRexARexBRIIARIIB

Identifiers

PMID33877398
OpenAlexW3155815658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.