ArticleApplied spectroscopy2021
Design Considerations for Discrete Frequency Infrared Microscopy Systems.
Article in Applied spectroscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed.
- Transfer-Matrix Framework for Modeling Mid-Infrared Vibrational Circular Dichroism Spectra.Analytical chemistry · 2026Article
- Rapid Vibrational Circular Dichroism Spectroscopy via Synchronized Photoelastic Modulator-Quantum Cascade Laser Integration.ACS measurement science au · 2025Article
- Exploring Feature Selection with Deep Learning for Kidney Tissue Microarray Classification Using Infrared Spectral Imaging.Bioengineering (Basel, Switzerland) · 2025Article
- Benchtop IR Imaging of Live Cells: Monitoring the Total Mass of Biomolecules in Single Cells.Analytical chemistry · 2024Article
- Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging.Nature communications · 2023Article
- Phasor Representation Approach for Rapid Exploratory Analysis of Large Infrared Spectroscopic Imaging Data Sets.Analytical chemistry · 2023Article
- Digital Histopathology by Infrared Spectroscopic Imaging.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023Review
- Cell Phase Identification in a Three-Dimensional Engineered Tumor Model by Infrared Spectroscopic Imaging.Analytical chemistry · 2023Article
- Resolution Limit in Infrared Chemical Imaging.The journal of physical chemistry. C, Nanomaterials and interfaces · 2022Article
- On the Limit of Detection in Infrared Spectroscopic Imaging.Applied spectroscopy · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Discrete frequency infrared chemical imaging is transforming the practice of microspectroscopy by enabling a diversity of instrumentation and new measurement capabilities. While a variety of hardware implementations have been realized, design considerations that are unique to infrared (IR) microscopes have not yet been compiled in literature. Here, we describe the evolution of IR microscopes, provide rationales for design choices, and catalog some major considerations for each of the optical components in an imaging system. We analyze design choices that use these components to optimize performance, under their particular constraints, while providing illustrative examples. We then summarize a framework to assess the factors that determine an instrument's performance mathematically. Finally, we provide a validation approach by enumerating performance metrics that can be used to evaluate the capabilities of imaging systems or suitability for specific intended applications. Together, the presented concepts and examples should aid in understanding available instrument configurations, while guiding innovations in design of the next generation of IR chemical imaging spectrometers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.