ArticleRadiology2021
Four-dimensional Multiphase Steady-State MRI with Ferumoxytol Enhancement: Early Multicenter Feasibility in Pediatric Congenital Heart Disease.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in Radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Cardiac Magnetic Resonance Imaging to Determine Single Ventricle Function in a Pediatric Population is Feasible in a Large Trial Setting: Experience from the Single Ventricle Reconstruction Trial Longitudinal Follow up.Pediatric cardiology · 2023Trial
- Performance of Free-Running Cardiac and Respiratory Motion-Resolved Whole-Heart 5D MRI in Congenital Heart Disease Patients Using a Gadolinium Enhanced Fast-Interrupted Steady-State Sequence.Journal of magnetic resonance imaging : JMRI · 2026Article
- Rapid Visualization of Valves and Myocardium Using Volume Rendering of 3D Cardiac MRI, 4D Cine, and 4D Flow Images.Radiology. Cardiothoracic imaging · 2026Article
- Case Report: Atrial baffles of pulmonary and systemic veins for the anatomic and physiologic repair of left atrial isomerism heterotaxy-pre- and post-operative three-dimensional reconstructions of two mirror-image pediatric hearts.Frontiers in cardiovascular medicine · 2025Article
- Ferumoxytol-enhanced cardiovascular magnetic resonance imaging: applications and technical advances.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Review
- Enhancement of the lymphatic system following intravenous administration of ferumoxytol.Pediatric radiology · 2024Article
- Four-dimensional endocardial surface imaging with dynamic virtual reality rendering: a technical note.Translational pediatrics · 2024Review
- Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI.National science review · 2024Review
- Highly efficient free-breathing 3D whole-heart imaging in 3-min: single center study in adults with congenital heart disease.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- Ferumoxytol-Enhanced MRI in Children and Young Adults: State of the Art.AJR. American journal of roentgenology · 2023Article
- Free-breathing, Contrast Agent-free Whole-Heart MTC-BOOST Imaging: Single-Center Validation Study in Adult Congenital Heart Disease.Radiology. Cardiothoracic imaging · 2023Article
- Contemporary sequential segmental approach to congenital heart disease using four-dimensional magnetic resonance imaging with ferumoxytol: an illustrated editorial.Frontiers in cardiovascular medicine · 2023Review
- Ferumoxytol-Enhanced Cardiac Magnetic Resonance Angiography and 4D Flow: Safety and Utility in Pediatric and Adult Congenital Heart Disease.Children (Basel, Switzerland) · 2022Review
- Contrast-enhanced MR Angiography without Gadolinium-based Contrast Material: Clinical Applications Using Ferumoxytol.Radiology. Cardiothoracic imaging · 2022Article
- A Two-Photon Microimaging-Microdevice System for Four-Dimensional Imaging of Local Drug Delivery in Tissues.International journal of molecular sciences · 2021Article
- Reproducibility of circumferential strain on cine displacement encoding with stimulated echoes magnetic resonance imaging before and after contrast at 3T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceArticle
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Kim-Lien NguyenFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).ORCID 0000-0002-8854-2976
Reena M GhoshFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).
Lindsay M GriffinFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).ORCID 0000-0003-2401-1380
Takegawa YoshidaFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).ORCID 0000-0002-2767-7009
Arash BedayatFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).
Cynthia K RigsbyFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).ORCID 0000-0003-1224-2333
Mark A FogelFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).
Kevin K WhiteheadFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).
Peng HuFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).
J Paul FinnFrom the Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences (K.L.N., T.Y., A.B., P.H., J.P.F.), and Division of Cardiology (K.L.N.), David Geffen School of Medicine at UCLA, 300 Medical Plaza, B119, Los Angeles, CA 90095; VA Greater Los Angeles Healthcare System, Los Angeles, Calif (K.L.N.); Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pa (R.M.G., M.A.F., K.K.W.); Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital, Chicago, Ill (L.M.G., C.K.R.); and Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill (L.M.G., C.K.R.).ORCID 0000-0002-4534-7572
University of California, Los Angeles · USChildren's Hospital of Philadelphia · USNorthwestern University · US
Funding
CLINICAL PHARMACOLOGY TRAINING PROGRAMT32GM008562 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI WALTER K KRAFT, Scott A. Waldman · 1995 to 2026
$10.2MExpanding on a new paradigm for MRI in pediatric congenital heart diseaseR01HL127153 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTODOULOU, ANTHONY G, FINN, JOHN PAUL · 2015 to 2024
$6.1MFunctional Cardiovascular 4D MRI in Congenital Heart DiseaseR01HL115828 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MARKL, MICHAEL, RIGSBY, CYNTHIA K · 2012 to 2021
$5.2MFerumoxytol-Enhanced Cardiac MRI for Ischemic Heart DiseaseR01HL148182 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NGUYEN, KIM-LIEN T · 2020 to 2024
$3.8MAcute Imposition of Fontan Physiology in The Single Ventricle Patient: Effects on Fibrosis, Function and Drug InterventionR01HL149139 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI FOGEL, MARK A · 2020 to 2023
$3.0MPediatric Replacement of the Pulmonary Valve - TOF TrialR34HL142142 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI FOGEL, MARK A · 2018 to 2020
$816kTailoring Stress Cardiac MRI for Women with Ischemic Heart DiseaseI01CX001901 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI NGUYEN, KIM-LIEN T · 2019 to 2025
–CSRD VA I01 CX001901NHLBI NIH HHS R01 HL115828NHLBI NIH HHS R01 HL127153NHLBI NIH HHS R01 HL148182NHLBI NIH HHS R01 HL149139NHLBI NIH HHS R34 HL142142NIGMS NIH HHS T32 GM008562
Abstract
Background The value of MRI in pediatric congenital heart disease (CHD) is well recognized; however, the requirement for expert oversight impedes its widespread use. Four-dimensional (4D) multiphase steady-state imaging with contrast enhancement (MUSIC) is a cardiovascular MRI technique that uses ferumoxytol and captures all anatomic features dynamically. Purpose To evaluate multicenter feasibility of 4D MUSIC MRI in pediatric CHD. Materials and Methods In this prospective study, participants with CHD underwent 4D MUSIC MRI at 3.0 T or 1.5 T between 2014 and 2020. From a pool of 460 total studies, an equal number of MRI studies from three sites (
Indexed as
ChildChild, PreschoolContrast MediaFeasibility StudiesFemaleFerrosoferric OxideHeart Defects, CongenitalHumansInfantMagnetic Resonance ImagingMaleProspective StudiesContrast MediaFerrosoferric Oxide
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.