Evidence map›Paper›PMID 33876913›Full record

ArticlePuerto Rico health sciences journal2021

Elimination of the Perinatal Transmission of HIV and Syphilis in Puerto Rico and Sustained Success since 2007: Convergence of Science, Women-Centered Care, and Policy.

Carmen D Zorrilla, Linnette Rodríguez-Figueroa, Sandra Miranda-De León, Bernardita López-Alvarado, Eileen Pérez, Silvia E Rabionet

Open access · greenAbstract read
In one paragraph

Article in Puerto Rico health sciences journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carmen D ZorrillaSchool of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Linnette Rodríguez-FigueroaGraduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Sandra Miranda-De LeónHIV/AIDS Surveillance Program, Puerto Rico Department of Health.
Bernardita López-AlvaradoHIV/AIDS Surveillance Program, Puerto Rico Department of Health.
Eileen PérezPerinatal HIV Program, Puerto Rico Department of Health.
Silvia E RabionetGraduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico; College of Pharmacy, Nova Southeastern University.
University of Puerto Rico, Medical Sciences Campus · PR

Funding

University of Puerto Rico Clinical Trials UnitUM1AI069415 · NIAID · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FEBO, IRMA LUZ, SANTANA-BAGUR, JORGE L. · 2012 to 2021
$15.2M
University of Puerto Rico Clinical Trials UnitU01AI069415 · NIAID · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ZORRILLA, CARMEN D · 2007 to 2011
$12.4M
University of Puerto Rico Mentoring Institute for HIV Mental Health ResearchR25MH083617 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ZORRILLA, CARMEN D · 2008 to 2020
$3.7M
NIAID NIH HHS U01 AI069415NIAID NIH HHS UM1 AI069415NIMH NIH HHS R25 MH083617
6 · The paper itself

Abstract

objectiveThere have been significant successes in the fight against HIV/AIDS due to the access to rapid HIV testing, interventions to reduce the mother-to-child transmission (MTCT) risk, potent and effective antiviral medications, and other biomedical prevention strategies. The purpose of this work is to demonstrate that Puerto Rico eliminated Mother-to-Child Transmission of HIV (MTCT) following the 2017 World Health Organization (WHO) criteria for validating the elimination of MTCT and Syphilis.

methodsExisting epidemiological data from Puerto Rico was used to document the elimination of MTCT and Syphilis. Data to calculate the indicators was obtained from the various divisions of the Puerto Rico Department of Health, including vital statistics, surveillance data, and programmatic outcomes.

resultsPuerto Rico eliminated MTCT and syphilis, according to the WHO indicators, earlier than other countries. We can trace the outcomes to 1994 using the incidence rate of perinatally-acquired HIV of <50/100,000; to 2007 using HIV perinatal transmission rates for non-breastfeeding countries (<2%), to 2008 using 90% of women receiving ART at delivery, and to 2005 using the incidence rate of congenital syphilis of <50/100,000.

conclusionNot only have we eliminated the MTCT of HIV and syphilis, but the efforts have been sustained since 2000. The elimination of transmission of infectious diseases requires the intersection of scientific feasibility, coordinated interventions, and political will, successfully attained in Puerto Rico.

Indexed as

Disease EradicationAdultFemaleHealth PolicyHIV InfectionsHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPuerto RicoSyphilisElimination of Mother to Child HIV TransmissionHIV and pregnancyHIV and SyphilisPerinatal HIV transmissionWomen-centered HIV Care

Identifiers

PMID33876913
PMCPMC8363176
OpenAlexW3154342171

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.