ArticleProceedings of the National Academy of Sciences of the United States of America2021
Topological defects produce kinks in biopolymer filament bundles.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Aggregation and structural phase transitions of semiflexible polymer bundles: A braided circuit topology approach.iScience · 2024Article
- Article
- Topological defects produce kinks in biopolymer filament bundles.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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6 authors.
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Abstract
Bundles of stiff filaments are ubiquitous in the living world, found both in the cytoskeleton and in the extracellular medium. These bundles are typically held together by smaller cross-linking molecules. We demonstrate, analytically, numerically, and experimentally, that such bundles can be kinked, that is, have localized regions of high curvature that are long-lived metastable states. We propose three possible mechanisms of kink stabilization: a difference in trapped length of the filament segments between two cross-links, a dislocation where the endpoint of a filament occurs within the bundle, and the braiding of the filaments in the bundle. At a high concentration of cross-links, the last two effects lead to the topologically protected kinked states. Finally, we explore, numerically and analytically, the transition of the metastable kinked state to the stable straight bundle.
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