Evidence map›Paper›PMID 33876744›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.

Hauke S Hillen, Dmitriy A Markov, Ireneusz D Wojtas, Katharina B Hofmann, Michael Lidschreiber, Andrew T Cowan, Julia L Jones, Dmitry Temiakov, Patrick Cramer, Michael Anikin

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Structures of pentatricopeptide repeat proteins.Acta crystallographica. Section F, Structural biology communications · 2026
    Review
  3. Article
  4. Transplantation ofMicrobiology (Reading, England) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. How RNases Shape Mitochondrial Transcriptomes.International journal of molecular sciences · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Hauke S HillenDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.ORCID 0000-0002-1206-0129
Dmitriy A MarkovDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Ireneusz D WojtasDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.ORCID 0000-0003-0704-9651
Katharina B HofmannDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.ORCID 0000-0002-0683-6277
Michael LidschreiberDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.ORCID 0000-0002-6740-2755
Andrew T CowanDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Julia L JonesDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Dmitry TemiakovDepartment of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107.ORCID 0000-0001-5497-3068
Patrick CramerDepartment of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany; patrick.cramer@mpibpc.mpg.de anikinmi@rowan.edu.ORCID 0000-0001-5454-7755
Michael AnikinDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084; patrick.cramer@mpibpc.mpg.de anikinmi@rowan.edu.
Rowan University · USMax Planck Institute for Biophysical Chemistry · DEThomas Jefferson University · USUniversitätsmedizin Göttingen · DE

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Andrew Chapman · 1995 to 2026
$94.8M
Molecular Mechanisms of Mitochondrial Transcription and ReplicationR35GM131832 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI Dmitry Temiakov · 2019 to 2026
$4.3M
A NEW HYBRID DIFFRACTOMETER FOR MACROMOLECULAR CRYSTALLOGRAPHY AND SAXS AT TJUS10OD017987 · OD · THOMAS JEFFERSON UNIVERSITY · PI CINGOLANI, GINO · 2014 to 2014
$600k
A High-Throughput Crystallization Platform at JeffersonS10OD023479 · OD · THOMAS JEFFERSON UNIVERSITY · PI CINGOLANI, GINO · 2019 to 2019
$94k
NCI NIH HHS P30 CA056036NIGMS NIH HHS R35 GM131832NIH HHS S10 OD017987NIH HHS S10 OD023479
6 · The paper itself

Abstract

Stabilization of messenger RNA is an important step in posttranscriptional gene regulation. In the nucleus and cytoplasm of eukaryotic cells it is generally achieved by 5' capping and 3' polyadenylation, whereas additional mechanisms exist in bacteria and organelles. The mitochondrial mRNAs in the yeast

Indexed as

3' Untranslated RegionsGenes, MitochondrialMembrane ProteinsNucleotide MotifsProtein BindingProtein DomainsRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteins3' Untranslated RegionsMembrane ProteinsRMD9 protein, S cerevisiaeRNA, MessengerSaccharomyces cerevisiae Proteinsgene expressionmitochondriaPAR-CLIPPPR proteinsprotein-RNA complex

Identifiers

PMID33876744
PMCPMC8054023
OpenAlexW3143899700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.