Evidence map›Paper›PMID 33876729›Full record

ArticleeLife2021

Bacterial-fungal interactions in the neonatal gut influence asthma outcomes later in life.

Rozlyn C T Boutin, Charisse Petersen, Sarah E Woodward, Antonio Serapio-Palacios, Tahereh Bozorgmehr, Rachelle Loo, Alina Chalanuchpong, Mihai Cirstea, Bernard Lo, Kelsey E Huus and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. From Fetus to Eight: the CHILD Cohort Study.American journal of epidemiology · 2024
    Article
  10. Article
  11. Review
  12. Gut Mycobiome and Asthma.Journal of fungi (Basel, Switzerland) · 2024
    Review
  13. Review
  14. The re-emerging role of linoleic acid in paediatric asthma.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  15. Review
  16. Commensal fungi in intestinal health and disease.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 1 country.

Rozlyn C T BoutinDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0003-1598-0104
Charisse PetersenMichael Smith Laboratories, University of British Columbia, Vancouver, Canada.
Sarah E WoodwardDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.ORCID http://orcid.org/0000-0002-6688-0595
Antonio Serapio-PalaciosMichael Smith Laboratories, University of British Columbia, Vancouver, Canada.
Tahereh BozorgmehrMichael Smith Laboratories, University of British Columbia, Vancouver, Canada.
Rachelle LooDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Alina ChalanuchpongDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Mihai CirsteaDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.ORCID http://orcid.org/0000-0003-4900-6385
Bernard LoDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Kelsey E HuusDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Weronika BarcikMichael Smith Laboratories, University of British Columbia, Vancouver, Canada.
Meghan B AzadChildren's Hospital Research Institute of Manitoba and Department of Pediatrics and Child Health, University of Manitoba, WinnipegMB, Canada.
Allan B BeckerChildren's Hospital Research Institute of Manitoba and Department of Pediatrics and Child Health, University of Manitoba, WinnipegMB, Canada.
Piush J MandhaneDepartment of Pediatrics, University of Alberta, Edmonton, Canada.
Theo J MoraesThe Hospital for Sick Children, Toronto, Canada.
Malcolm R SearsDepartment of Medicine, McMaster University, Hamilton, Canada.
Padmaja SubbaraoThe Hospital for Sick Children, Toronto, Canada.
Kelly M McNagnyDepartment of Biomedical Engineering, University of British Columbia, Vancouver, Canada.ORCID http://orcid.org/0000-0003-4737-3499
Stuart E TurveyDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
B Brett FinlayDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0001-5303-6128
University of British Columbia · CAChildren's Hospital Research Institute of Manitoba · CAHospital for Sick Children · CAMcMaster University · CAUniversity of Alberta · CAUniversity of Toronto · CA

Funding

AllerGen 12CHILDCIHR FDN-159935CIHR PJT-148484
6 · The paper itself

Abstract

Bacterial members of the infant gut microbiota and bacterial-derived short-chain fatty acids (SCFAs) have been shown to be protective against childhood asthma, but a role for the fungal microbiota in asthma etiology remains poorly defined. We recently reported an association between overgrowth of the yeast

Indexed as

AnimalsAsthmaBacteriaBacterial Physiological PhenomenaCase-Control StudiesChildChild, PreschoolGastrointestinal MicrobiomeHumansInfantMiceMice, Inbred C57BLPichiaSpecific Pathogen-Free Organismsasthmahumanimmunologyinflammationmedicinemicrobiotamousemycobiotapichia kudriavzevii

Identifiers

PMID33876729
PMCPMC8075585
OpenAlexW3155328394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.