Evidence map›Paper›PMID 33876410›Full record

SynthesisEating and weight disorders : EWD2022

Psychophysical chemosensory dysfunction in eating disorders: a qualitative systematic review.

Evelyn M Leland, Deborah X Xie, Vidyulata Kamath, Stella M Seal, Sandra Y Lin, Nicholas R Rowan

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Headache-Associated Phantosmia as a Harbinger of Lewy Body Dementia.The Journal of neuropsychiatry and clinical neurosciences · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Evelyn M LelandDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 601 N. Caroline St, 6th floor, Ste 6230, Baltimore, MD, 21287, USA.ORCID http://orcid.org/0000-0001-8491-7366
Deborah X XieDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 601 N. Caroline St, 6th floor, Ste 6230, Baltimore, MD, 21287, USA.ORCID http://orcid.org/0000-0002-3949-199X
Vidyulata KamathDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7711-3597
Stella M SealWelch Medical Library, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2838-4168
Sandra Y LinDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 601 N. Caroline St, 6th floor, Ste 6230, Baltimore, MD, 21287, USA.ORCID http://orcid.org/0000-0001-8959-1828
Nicholas R RowanDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 601 N. Caroline St, 6th floor, Ste 6230, Baltimore, MD, 21287, USA. nrowan1@jhmi.edu.ORCID http://orcid.org/0000-0003-1296-2648
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with chemosensory dysfunction experience significant quality of life disruptions, including reduced enjoyment of eating. While chemosensory dysfunction has been associated with eating disorders, the relationship is poorly understood. This systematic review aims to characterize psychophysical gustation and olfaction in patients with eating disorders.

methodsSystematic review of investigations assessing psychophysical chemosensory function in patients with organic eating disorders.

results26 studies were included. Five studies assessed both chemosenses, while 12 and 9 assessed exclusively gustation or olfaction, respectively. In total, 779 patients were included [72.4% anorexia nervosa (AN), 26.7% bulimia nervosa (BN), 0.8% combined AN/BN]. Patients with eating disorders experienced rates of hypogeusia up to 87% in AN and 84.6% in BN. There was evidence for alterations in psychophysical olfaction, but orientation of trends were less clear. Chemosensory dysfunction was more evident in AN patients. Treatment correlated with improved chemosensory function.

conclusionsDespite heterogeneity in study methodology and results, this review demonstrates that patients with eating disorders experience some degree of chemosensory dysfunction, particularly in gustation. This symptomatology overlaps with those experienced by patients with other causes of chemosensory impairment. These findings suggest potential broad psychosocial, dietary, and mental health implications in patient populations experiencing chemosensory dysfunction. LEVEL OF EVIDENCE: Level II.

Indexed as

Anorexia NervosaBulimia NervosaFeeding and Eating DisordersDietHumansQuality of LifeAnorexia nervosaBulimia nervosaFeeding and eating disordersSmellTaste

Identifiers

PMID33876410
OpenAlexW3156004548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.