Evidence map›Paper›PMID 33876375›Full record

ArticleMolecular biology reports2021

Comparative genomics of invasive Streptococcus pneumoniae CC320/271 serotype 19F/19A before the introduction of pneumococcal vaccine in India.

Rosemol Varghese, Ayyanraj Neeravi, Jobin John Jacob, Karthick Vasudevan, Jones Lionel Kumar, Nithya Subramanian, Balaji Veeraraghavan

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Article in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Human vaccines & immunotherapeutics · 2025
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rosemol VargheseDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Ayyanraj NeeraviDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Jobin John JacobDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Karthick VasudevanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Jones Lionel KumarDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Nithya SubramanianDepartment of Child Health, Christian Medical College, Vellore, India.
Balaji VeeraraghavanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India. vbalaji@cmcvellore.ac.in.ORCID http://orcid.org/0000-0002-8662-4257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of multi drug resistant clone CC320 serotype19F/19A and their capsular (cps) antigenic variants due to selective pressures such as vaccine had been reported worldwide. Hence, it is important to identify the prevalent clones, sequence types and cps variants of serotype 19F/19A in India, where PCV13 has been recently introduced. Multi-locus sequence typing (MLST) was performed for all (n = 21) invasive S. pneumoniae isolates of serotype 19A (n = 5) and 19F (n = 16) collected between the years 2012 and 2018 from children less than 5 years. The genome characterization by whole genome sequencing for the Sequence types (STs) 320 and 271(n = 7) were performed and compared with another six Indian WGSs of similar STs available from the GPS platform. The predominant STs in the serotype 19F/19A study isolates were of CC320: ST 320, 236 and 271, associated with PMEN clone Taiwan

Indexed as

Penicillin ResistanceSerogroupChild, PreschoolGenomicsHumansIndiaMultilocus Sequence TypingPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeWhole Genome Sequencing13-valent pneumococcal vaccinePneumococcal VaccinesCC320IndiaPenicillin binding proteinsPenicillin resistanceSerotype 19S. pneumoniae

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.