Evidence map›Paper›PMID 33876219›Full record

ArticleBlood2021

Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia.

Steven D Mittelman, Jiyoon Kim, Gordana Raca, Gang Li, Matthew J Oberley, Etan Orgel

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Frontiers in oncology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Steven D MittelmanDivision of Pediatric Endocrinology, University of California, Los Angeles (UCLA) Children's Discovery and Innovation Institute, David Geffen School of Medicine, and.ORCID 0000-0003-2867-1298
Jiyoon KimDepartment of Biostatistics and Computational Medicine, Jonathan and Karin Fielding School of Public Health, UCLA, Los Angeles, CA.
Gordana RacaCenter for Personalized Medicine, Children's Hospital Los Angeles, Los Angeles, CA.ORCID 0000-0002-3521-9585
Gang LiDepartment of Biostatistics and Computational Medicine, Jonathan and Karin Fielding School of Public Health, UCLA, Los Angeles, CA.
Matthew J OberleyDepartment of Pathology and Laboratory Medicine and.ORCID 0000-0001-6419-2513
Etan OrgelDepartment of Pediatrics, Keck School of Medicine of the University of Southern California, Los Angeles, CA; and.ORCID 0000-0002-1487-6818
UCLA Health · USUniversity of Southern California · USUniversity of California, Los Angeles · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative SupplementP40OD024628 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Joe H. Simmons · 2017 to 2026
$15.7M
Pilot ProjectP30GM114731 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI MCEVER, RODGER PAUL · 2016 to 2020
$6.5M
Adipocytes are Important Players in the Acute Lymphoblastic Leukemia MicroenvironmentR01CA201444 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MITTELMAN, STEVEN DAVID · 2016 to 2020
$1.9M
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCATS NIH HHS UL1 TR001881NCI NIH HHS P30 CA016042NCI NIH HHS P50 CA211015NCI NIH HHS R01 CA201444NIGMS NIH HHS P30 GM114731NIH HHS P40 OD024628
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adipose TissueAdolescentChildCohort StudiesFemaleGene RearrangementHispanic or LatinoHumansMaleObesityPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, CytokineCRLF2 protein, humanReceptors, Cytokine

Identifiers

PMID33876219
PMCPMC8288656
OpenAlexW3154608105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.