Evidence map›Paper›PMID 33876178›Full record

ArticleThe American journal of clinical nutrition2021

Gestational weight gain in 4 low- and middle-income countries and associations with birth outcomes: a secondary analysis of the Women First Trial.

Melissa S Bauserman, Carla M Bann, K Michael Hambidge, Ana L Garces, Lester Figueroa, Jamie L Westcott, Jackie K Patterson, Elizabeth M McClure, Vanessa R Thorsten, Sumera Ali Aziz and 11 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Observational
  9. Article
  10. The effect of advanced maternal age and gestational weight gain on newborns.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  11. Article
  12. Article
  13. The importance of nutrition in pregnancy and lactation: lifelong consequences.American journal of obstetrics and gynecology · 2022
    Review
  14. Article
  15. Article
  16. Maternal weight gain and birth weight.Journal of the Chinese Medical Association : JCMA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 5 countries.

Melissa S BausermanDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-4992-9895
Carla M BannRTI International, Durham, NC, USA.
K Michael HambidgeSection of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Ana L GarcesINCAP (Institute of Nutrition of Central America and Panama), Guatemala City, Guatemala.
Lester FigueroaINCAP (Institute of Nutrition of Central America and Panama), Guatemala City, Guatemala.
Jamie L WestcottSection of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Jackie K PattersonDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Elizabeth M McClureRTI International, Durham, NC, USA.
Vanessa R ThorstenRTI International, Durham, NC, USA.
Sumera Ali AzizDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Richard J DermanDepartment of Global Affairs, Thomas Jefferson University, Philadelphia, PA, USA.
Veena HerekarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Manjunath SomannavarKLE Academy of Higher Education and Research's Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Marion W Koso-ThomasNational Institute of Child Health and Human Development/NIH, Bethesda, MD, USA.
Adrien L LokangakaKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
Antoinette K TshefuKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
Nancy F KrebsSection of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Carl L BoseDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-8727-8640
Women First Preconception Trial Study Group
RTI International · USUniversity of Colorado Denver · USUniversity of North Carolina at Chapel Hill · USAga Khan University · PKInstitute of Nutrition of Central America and Panama · GTJawaharlal Nehru Medical College · INMinistry of Public Health · CDColumbia University · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USThomas Jefferson University · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women'sand Children's Health Through ResearchUG1HD076465 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELISSA SCHWEIKHART BAUSERMAN · 2018 to 2026
$5.6M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
NICHD NIH HHS UG1 HD076465NICHD NIH HHS UG1 HD076474NIDDK NIH HHS P30 DK056350NIH HHS 076474
6 · The paper itself

Abstract

backgroundAdequate gestational weight gain (GWG) is essential for healthy fetal growth. However, in low- and middle-income countries, where malnutrition is prevalent, little information is available about GWG and how it might be modified by nutritional status and interventions.

objectiveWe describe GWG and its associations with fetal growth and birth outcomes. We also examined the extent to which prepregnancy BMI, and preconception and early weight gain modify GWG, and its effects on fetal growth.

methodsThis was a secondary analysis of the Women First Trial, including 2331 women within the Democratic Republic of Congo (DRC), Guatemala, India, and Pakistan, evaluating weight gain from enrollment to ∼12 weeks of gestation and GWG velocity (kg/wk) between ∼12 and 32 weeks of gestation. Adequacy of GWG velocity was compared with 2009 Institute of Medicine recommendations, according to maternal BMI. Early weight gain (EWG), GWG velocity, and adequacy of GWG were related to birth outcomes using linear and Poisson models.

resultsGWG velocity (mean ± SD) varied by site: 0.22 ± 0.15 kg/wk in DRC, 0.30 ± 0.23 in Pakistan, 0.31 ± 0.14 in Guatemala, and 0.39 ± 0.13 in India, (P <0.0001). An increase of 0.1 kg/wk in maternal GWG was associated with a 0.13 cm (95% CI: 0.07, 0.18, P <0.001) increase in birth length and a 0.032 kg (0.022, 0.042, P <0.001) increase in birth weight. Compared to women with inadequate GWG, women who had adequate GWG delivered newborns with a higher mean length and weight: 47.98 ± 2.04 cm compared with 47.40 ± 2.17 cm (P <0.001) and 2.864 ± 0.425 kg compared with 2.764 ± 0.418 kg (P <0.001). Baseline BMI, EWG, and GWG were all associated with birth length and weight.

conclusionsThese results underscore the importance of adequate maternal nutrition both before and during pregnancy as a potentially modifiable factor to improve fetal growth.

Indexed as

Developing CountriesGestational Weight GainPregnancy OutcomeAdultBirth WeightFemaleGlobal HealthHumansInfant, NewbornPovertyPregnancyYoung Adultdeveloping countriesfetal developmentgestational weight gaininfant nutrition disorderslow birth weightmalnutritionnutrition during pregnancy

Identifiers

PMID33876178
PMCPMC8326045
OpenAlexW3156638103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.