ArticleObesity medicine2021
Does higher body mass index increase COVID-19 severity? A systematic review and meta-analysis.
Article in Obesity medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- COVID-19 infection and body weight: A deleterious liaison in a J-curve relationship.Obesity research & clinical practicePooled it
- Alteration of the Gut-Lung Axis After Severe COVID-19 Infection and Modulation Through Probiotics: A Randomized, Controlled Pilot Study.Nutrients · 2024Trial
- Predictive diagnostic models for newly diagnosed diabetes mellitus in moderate to severe COVID-19: the role of TyG Index, BMI, and inflammatory markers.BMC endocrine disorders · 2025Article
- Democratic quality and excess mortality during the COVID-19 pandemic.Scientific reports · 2024Article
- Risk factors for SARS-CoV-2 infection: a test-negative case-control study with additional population controls in Norway.BMJ open · 2024Article
- Review
- Body-mass index COVID-19 severity: A systematic review of systematic reviews.Journal of family medicine and primary care · 2022Article
- Association of obesity with COVID-19 diseases severity and mortality: A meta-analysis of studies.Obesity medicine · 2022Article
- Survival analysis based on body mass index in patients with Covid-19 admitted to the intensive care unit of Amir Al-Momenin Hospital in Arak - 2021.Obesity medicine · 2022Article
- COVID-19 Mortality in Europe, by Latitude and Obesity Status: A Geo-Spatial Analysis in 40 Countries.Nutrients · 2022Article
- Assessment of Physical Disability After Three Months in Patients Recovered From COVID-19: A Cross-Sectional Study.Cureus · 2022Article
- Neck Circumference Predicts Mortality in Hospitalized COVID-19 Patients.Infectious disease reports · 2021Article
- Colon ischemia in patients with severe COVID-19: a single-center retrospective cohort study of 20 patients.International journal of colorectal disease · 2021Article
- Modifiable Risk Factors for SARS-CoV-2.Integrative medicine (Encinitas, Calif.) · 2021Article
- Food consumption changes among teachers during the COVID-19 pandemic.Obesity medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObesity and higher BMI is one of the leading comorbidities to increase the risk of COVID-19 severity. This paper presents a systematic review and meta-analysis estimating the effects of overweight and obesity on COVID-19 disease severity.
methodTwo electronic databases (Medline and Cochrane library) and one grey literature database (Grey Literature Report) were searched. The risks of bias of the selected studies were assessed by using the Navigation Guide method for human data. Both random and fixed effect meta-analyses were determined using Review Manager (RevMan) software version 5.4.
resultsAfter initial screening, 12 studies were fulfilled the eligibility criteria, comprising a total of 405359 patients, and included in the systematic review. The pooled risk of COVID-19 severity was 1.31 times higher based on both fixed and random effect model among those overweight patients,
conclusionOverweight and obesity are found to be risk factors for disease severity of COVID-19 patients. However, further assessment of metabolic parameters is required to estimate the risk factors of COVID-19 patients and understanding the mechanism between COVID-19 and body mass index.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.