ArticleNature genetics2021
Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan.
Article in Nature genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed.
- Bony fish genomes: Status and gaps.Journal of fish biology · 2026Review
- Subterranean Traits of the Visual System in Mandarin Voles (Lasiopodomys mandarinus): Structural Remodeling and Functional Degeneration.Integrative zoology · 2026Article
- De novo Genome Assembly, Annotation, and Comparative Analysis of the Lined Sole Achirus lineatus as a Resource for Evolutionary and Environmental Genomics.Marine biotechnology (New York, N.Y.) · 2026Article
- Article
- Integrated Histological, Ultrastructural, Lectin and Immunohistochemical Characterization of the Senegalese sole (Animals : an open access journal from MDPI · 2026Article
- Gmppb-mutant mice exhibit dystroglycanopathy symptoms that are rescued with GSK3β inhibition or AAV-mediated GMPPB gene replacement.Nature communications · 2026Article
- The thermodynamic opportunities hypothesis: Metabolic temperature insensitivity across flatfish species.Science advances · 2026Article
- Stable genome structures in living fossil fishes.Genome research · 2026Article
- Assembly, Characterization, and Phylogenetic Insights from the Complete Mitochondrial Genome ofBiology · 2026Article
- Full-length hybrid transcriptome of the olfactory rosette in Senegalese sole (Solea senegalensis): an essential genomic resource for improving reproduction on farms.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025Article
- Chromosome-level genome assembly of starry flounder (Platichthys stellatus).Scientific data · 2025Article
- Chromosome-level reference genome assembly of the gyrfalcon (Falco rusticolus) and population genomics offer insights into the falcon population in Mongolia.Scientific reports · 2025Article
- Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution.BMC genomics · 2025Article
- Comparison of muscle structure and transcriptome analysis of eyed-side muscle and blind-side muscle inZooKeys · 2025Review
- Advances in biotechnology and breeding innovations in China's marine aquaculture.Advanced biotechnology · 2024Review
- Decoding the fish genome opens a new era in important trait research and molecular breeding in China.Science China. Life sciences · 2024Review
- Diverse Origins of Near-Identical Antifreeze Proteins in Unrelated Fish Lineages Provide Insights Into Evolutionary Mechanisms of New Gene Birth and Protein Sequence Convergence.Molecular biology and evolution · 2024Article
- Phylogenomic and comparative genomic analyses support a single evolutionary origin of flatfish asymmetry.Nature genetics · 2024Article
- Reply to: Phylogenomic and comparative genomic analyses support a single evolutionary origin of flatfish asymmetry.Nature genetics · 2024Article
- Genome sequencing and analysis of black flounder (Paralichthys orbignyanus) reveals new insights into Pleuronectiformes genomic size and structure.BMC genomics · 2024Article
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26 authors.
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Abstract
The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.
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