Evidence map›Paper›PMID 33875765›Full record

ArticleScientific reports2021

Optimisation of T2 and T2* sequences in MRI for better quantification of iron on transfused dependent sickle cell patients.

Azza Ahmed, Amani Baldo, A Sulieman, Hind Mirghani, Fouad A Abolaban, I I Suliman, Isam Salih

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Elucidating Iron Metabolism through Molecular Imaging.Current issues in molecular biology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Azza AhmedSudan Atomic Energy Commission, Al Gamah Street, P. O. Box 3001, Khartoum, Sudan. azzasabo@hotmail.com.
Amani BaldoJaffar Bin Auf Paediatric Hospital, Hosptials Road, Khartoum, Sudan.
A SuliemanRadiology and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, P. O. Box 422, Alkharj, 11942, Saudi Arabia.
Hind MirghaniJaffar Bin Auf Paediatric Hospital, Hosptials Road, Khartoum, Sudan.
Fouad A AbolabanNuclear Engineering Department, Faculty of Engineering, King Abdulaziz University, P. O. Box 80221, Jeddah, 21589, Saudi Arabia.
I I SulimanSudan Atomic Energy Commission, Al Gamah Street, P. O. Box 3001, Khartoum, Sudan.
Isam SalihSudan Atomic Energy Commission, Al Gamah Street, P. O. Box 3001, Khartoum, Sudan. isamsalih@gmail.com.
Prince Sattam Bin Abdulaziz University · SASudan Medical Specialization Board · SDImam Mohammad ibn Saud Islamic University · SAKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to investigate the effect of different shim techniques, voxel sizes, and repetition time (TR) on using theT2 and T2* sequences to determine their optimum settings to investigate the quantification of iron in transfused dependent sickle cell patients. The effect of each of these parameters was investigated on phantoms of different Gadolinium (Gd) concentrations, on 10 volunteers and 25 patients using a1 5T MRI Philips scanner. No significant difference between the three shim techniques was noticed in either T2 or T2* sequence measurements. Pixel sizes of 1 × 1 and 2 × 2 mm provided optimum results for T2 measurements. At 1 × 1 mm pixel size the T2* measurements experienced less error in measurements than the size of 2.5 × 2.5 mm used in the literature. Even though the slice thickness variation did not provide any changes in T2 measurements, the 12 mm provided optimum T2* measurements. TR variation did not yield significant changes on either T2 or T2* measurements. These results indicate that both T2 and T2* sequences can be further improved by providing more reliable measurements and reducing acquisition time.

Indexed as

Anemia, Sickle CellErythrocytes, AbnormalGadoliniumHumansIronMagnetic Resonance ImagingPhantoms, ImagingGadoliniumIron

Identifiers

PMID33875765
PMCPMC8055987
OpenAlexW3155848888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.