Evidence map›Paper›PMID 33875581›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cargo competition for a dimerization interface restricts and stabilizes a bacterial protease adaptor.

Nathan J Kuhlmann, Dylan Doxsey, Peter Chien

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Structure of phosphorylated-like RssB, the adaptor delivering σThe Journal of biological chemistry · 2023
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nathan J KuhlmannDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003.
Dylan DoxseyDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003.ORCID 0000-0002-4092-3112
Peter ChienDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003; pchien@umass.edu.ORCID 0000-0001-6733-1478

Funding

Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
Regulated Proteolysisin Bacteria Development and Stress ResponseR35GM130320 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Peter Chien · 2019 to 2026
$3.4M
Cellular Engineering Biotechnology Training ProgramT32GM108556 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HARDY, JEANNE ANN, PEYTON, SHELLY R. · 2015 to 2019
$766k
NIGMS NIH HHS R35 GM130320NIGMS NIH HHS T32 GM108556NIGMS NIH HHS T32 GM135096
6 · The paper itself

Abstract

Bacterial protein degradation is a regulated process aided by protease adaptors that alter specificity of energy-dependent proteases. In

Indexed as

Bacterial ProteinsCaulobacter crescentusCell CycleCell Cycle ProteinsDimerizationDNA-Binding ProteinsEndopeptidase ClpEscherichia coli ProteinsPeptide HydrolasesProtein BindingProtein TransportProteolysisTranscription FactorsBacterial ProteinsCell Cycle ProteinsDNA-Binding ProteinsEndopeptidase ClpEscherichia coli ProteinsPeptide HydrolasesRcdA protein, E coliTranscription FactorsAAA+adaptor proteincell cycleClpXPproteolysis

Identifiers

PMID33875581
PMCPMC8092595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.