Evidence map›Paper›PMID 33875480›Full record

ArticleGenome research2021

Identification and characterization of centromeric sequences in

Owen K Smith, Charles Limouse, Kelsey A Fryer, Nicole A Teran, Kousik Sundararajan, Rebecca Heald, Aaron F Straight

Open access · greenAbstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  9. Pan-centromere reveals widespread centromere repositioning of soybean genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Owen K SmithDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California 94305-5307, USA.
Charles LimouseDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California 94305-5307, USA.
Kelsey A FryerDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California 94305-5307, USA.
Nicole A TeranDepartment of Genetics, Stanford University School of Medicine, Stanford, California 94305-5120, USA.
Kousik SundararajanDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California 94305-5307, USA.
Rebecca HealdDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720-3200, USA.
Aaron F StraightDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California 94305-5307, USA.ORCID 0000-0001-5885-7881
Stanford University · USUniversity of California, Berkeley · US

Funding

Mechanisms of mitosis and size control in XenopusR35GM118183 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALD, REBECCA W · 2016 to 2025
$8.2M
Mechanisms of Kinetochore AssemblyR01GM074728 · NIGMS · STANFORD UNIVERSITY · PI Aaron F Straight · 2005 to 2026
$6.6M
Molecular Pharmacology Training GrantT32GM113854 · NIGMS · STANFORD UNIVERSITY · PI MOCHLY-ROSEN, DARIA · 2015 to 2019
$1.1M
NIGMS NIH HHS R01 GM074728NIGMS NIH HHS R35 GM118183NIGMS NIH HHS T32 GM113854
6 · The paper itself

Abstract

Centromeres play an essential function in cell division by specifying the site of kinetochore formation on each chromosome for mitotic spindle attachment. Centromeres are defined epigenetically by the histone H3 variant Centromere Protein A (Cenpa). Cenpa nucleosomes maintain the centromere by designating the site for new Cenpa assembly after dilution by replication. Vertebrate centromeres assemble on tandem arrays of repetitive sequences, but the function of repeat DNA in centromere formation has been challenging to dissect due to the difficulty in manipulating centromeres in cells.

Indexed as

CentromereNucleosomesAnimalsCentromere Protein AChromatinRepetitive Sequences, Nucleic AcidXenopus laevisCentromere Protein AChromatinNucleosomes

Identifiers

PMID33875480
PMCPMC8168581
OpenAlexW3156092084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.