ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2021
Treatment burden for patients with multimorbidity: cross-sectional study with exploration of a single-item measure.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
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Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Measuring treatment burden in people with Type 2 Diabetes Mellitus (T2DM): a mixed-methods systematic review.BMC primary care · 2024Pooled it
- Influence of health-system change on treatment burden: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Pooled it
- A mixed-methods systematic review of nurse-led interventions for people with multimorbidity.Journal of advanced nursing · 2022Pooled it
- Pill burden and health-related quality of life across dialysis modalities: a multimodal assessment using KDQOL-36 and eQ-5D-5L.Renal failure · 2026Article
- Digital health technology burden and frustration among patients with multimorbidity.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Health Literacy and Chronic Disease Self-Efficacy Among Older Adults with Multimorbidity: Evidence from Low-Resource Context.Healthcare (Basel, Switzerland) · 2026Article
- Advance care planning for patients with advanced multiple long-term conditions: a qualitative thematic analysis of health and social care professionals' perspectives.BMC palliative care · 2026Article
- Understanding Remission of Long-Term Conditions Through Electronic Health Records: Scoping Review.Journal of medical Internet research · 2026Article
- Article
- From daily burden to scheduled protection: the "vaccine-like" shift in hypertension.Journal of human hypertension · 2026Review
- How eight health risks and chronic conditions relate: identifying associations and profiling characteristics of multiple health risk factors among 14 disease groups and 30 common chronic conditions in Denmark.Scandinavian journal of public health · 2026Article
- Time toxicity in chronic disease comorbidity care: A concept analysis using Walker and Avant's approach.International journal of nursing sciences · 2026Article
- Physician Characteristics Associated with Prioritizing Treatment Burden in Outpatient Care for Older Adults with Multimorbidity.JMA journal · 2026Article
- The association between treatment burden and quality of life in older adults with multimorbidity: the mediating role of personal mastery and the moderating role of social support-a cross-sectional study in China.Frontiers in public health · 2026Article
- Unraveling the pathway from treatment burden to holistic health status in older adults with complex multimorbidity: the mediating roles of stress adaptation and depressive symptoms.Frontiers in public health · 2026Article
- Identifying Digital Health Technology Engagement and Frustration Phenotypes in Patients with Multiple Chronic Conditions: Evidences from a Nationally Representative Cross-Sectional Study.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Approaches to characterising multimorbidity in older people accessing hospital care: a scoping review.European geriatric medicine · 2025Article
- Article
- Multimorbidity patterns of mental disorders and physical diseases of adults in northeast China: a cross-sectional network analysis.Epidemiology and psychiatric sciences · 2025Article
- Perceived treatment burden and health-related quality of life in association with healthcare utilisation among patients attending multiple outpatient clinics.Health and quality of life outcomes · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatment burden is the effort required of patients to look after their health, and the impact this has on their wellbeing. Quantitative data on treatment burden for patients with multimorbidity are sparse, and no single-item treatment burden measure exists.
aimTo determine the extent of, and associations with, high treatment burden among older adults with multimorbidity, and to explore the performance of a novel single-item treatment burden measure. DESIGN AND
settingCross-sectional postal survey via general practices in Dorset, UK.
methodPatients ≥55 years, living at home, with three or more long-term conditions (LTCs) were identified by practices. Treatment burden was measured using the Multimorbidity Treatment Burden Questionnaire. Data collected were sociodemographics, LTCs, medications, and characteristics including health literacy and financial resource. Associations with high treatment burden were investigated via logistic regression. Performance of a novel single-item measure of treatment burden was also evaluated.
resultsA total of 835 responses were received (response rate 42%) across eight practices. Patients' mean age was 75 years, 55% were female (
conclusionHigh treatment burden was relatively common, underlining the importance of minimising avoidable burden. More vulnerable patients, with less capacity to manage, are at greater risk of being overburdened. Further development of a single-item treatment burden measure is required.
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